Effect of Tobacco-specific Nitrosamines on MUC5AC Expression in Human Airway Epithelial Cells
Background and Objectives Nicotine is oxidized into tobacco-specific nitrosamines (TSNAs; NAB, NAT, NNN, NNAL, NNK) at high temperature and high pressure. TSNAs are associated with airway diseases characterized by mucus hypersecretion as a major pathophysiologic phenomenon. The aim of study is to in...
Main Authors: | Soyoung Kwak, Yoon Seok Choi, Hyung Gyun Na, Chang Hoon Bae, Si-Youn Song, Yong-Dae Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
Korean Rhinologic Society
2020-05-01
|
Series: | Journal of Rhinology |
Subjects: | |
Online Access: | http://www.j-rhinology.org/upload/pdf/jr-2019-00301.pdf |
Similar Items
-
Clusterin Induces MUC5AC Expression via Activation of NF-κB in Human Airway Epithelial Cells
by: Chang Hoon Bae, et al.
Published: (2018-06-01) -
Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma
by: Tomoko Tajiri, et al.
Published: (2022-04-01) -
Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells
by: Nathalie Baumlin, et al.
Published: (2023-01-01) -
Lysophosphatidylserine Induces MUC5AC Production via the Feedforward Regulation of the TACE-EGFR-ERK Pathway in Airway Epithelial Cells in a Receptor-Independent Manner
by: Myeong Seong Sim, et al.
Published: (2022-03-01) -
Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas
by: Onur Oral, et al.
Published: (2020-01-01)