COVID-19 and Neurological Manifestations
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a newly emerged coronavirus, has sparked a global pandemic with its airborne transmission and ability to infect with asymptomatic patients. The pathophysiology is thought to relate to the binding of angiotensin converting enzyme 2 (ACE2)...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/13/8/1137 |
| _version_ | 1797585290018160640 |
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| author | Kathleen Forero Raghad Buqaileh Clare Sunderman Wissam AbouAlaiwi |
| author_facet | Kathleen Forero Raghad Buqaileh Clare Sunderman Wissam AbouAlaiwi |
| author_sort | Kathleen Forero |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a newly emerged coronavirus, has sparked a global pandemic with its airborne transmission and ability to infect with asymptomatic patients. The pathophysiology is thought to relate to the binding of angiotensin converting enzyme 2 (ACE2) receptors in the body. These receptors are widely expressed in various body organs such as the lungs, the heart, the gastrointestinal tract (GIT), and the brain. This article reviews the current knowledge on the symptoms of coronavirus disease 2019 (COVID-19), highlighting the neurological symptoms that are associated with COVID-19, and discussing the possible mechanisms for SARS-CoV-2 virus infection in the body. |
| first_indexed | 2024-03-11T00:05:06Z |
| format | Article |
| id | doaj.art-136462f3e09e4fd49fa66befce036296 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T00:05:06Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-136462f3e09e4fd49fa66befce0362962023-11-19T00:26:13ZengMDPI AGBrain Sciences2076-34252023-07-01138113710.3390/brainsci13081137COVID-19 and Neurological ManifestationsKathleen Forero0Raghad Buqaileh1Clare Sunderman2Wissam AbouAlaiwi3Department of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USADepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USADepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USADepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a newly emerged coronavirus, has sparked a global pandemic with its airborne transmission and ability to infect with asymptomatic patients. The pathophysiology is thought to relate to the binding of angiotensin converting enzyme 2 (ACE2) receptors in the body. These receptors are widely expressed in various body organs such as the lungs, the heart, the gastrointestinal tract (GIT), and the brain. This article reviews the current knowledge on the symptoms of coronavirus disease 2019 (COVID-19), highlighting the neurological symptoms that are associated with COVID-19, and discussing the possible mechanisms for SARS-CoV-2 virus infection in the body.https://www.mdpi.com/2076-3425/13/8/1137coronavirusCOVID-19ACE2neurologycilia |
| spellingShingle | Kathleen Forero Raghad Buqaileh Clare Sunderman Wissam AbouAlaiwi COVID-19 and Neurological Manifestations Brain Sciences coronavirus COVID-19 ACE2 neurology cilia |
| title | COVID-19 and Neurological Manifestations |
| title_full | COVID-19 and Neurological Manifestations |
| title_fullStr | COVID-19 and Neurological Manifestations |
| title_full_unstemmed | COVID-19 and Neurological Manifestations |
| title_short | COVID-19 and Neurological Manifestations |
| title_sort | covid 19 and neurological manifestations |
| topic | coronavirus COVID-19 ACE2 neurology cilia |
| url | https://www.mdpi.com/2076-3425/13/8/1137 |
| work_keys_str_mv | AT kathleenforero covid19andneurologicalmanifestations AT raghadbuqaileh covid19andneurologicalmanifestations AT claresunderman covid19andneurologicalmanifestations AT wissamaboualaiwi covid19andneurologicalmanifestations |