Associations between Gilbert’s syndrome and personality characteristics
Abstract Objective Gilbert’s syndrome (GS) is a benign genetic disorder that is characterized by intermittent mild jaundice in which the liver doesn’t process bilirubin properly. The aim of this study was to determine whether GS patients have a different personality structure and if there are assoc...
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| Format: | Article |
| Language: | English |
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Associação de Psiquiatria do Rio Grande do Sul
2021-04-01
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| Series: | Trends in Psychiatry and Psychotherapy |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892021000200151&tlng=en |
| _version_ | 1818731535346434048 |
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| author | Tolga Düzenli Özgür Maden Alpaslan Tanoğlu Mustafa Kaplan Yusuf Yazgan |
| author_facet | Tolga Düzenli Özgür Maden Alpaslan Tanoğlu Mustafa Kaplan Yusuf Yazgan |
| author_sort | Tolga Düzenli |
| collection | DOAJ |
| description | Abstract Objective Gilbert’s syndrome (GS) is a benign genetic disorder that is characterized by intermittent mild jaundice in which the liver doesn’t process bilirubin properly. The aim of this study was to determine whether GS patients have a different personality structure and if there are associations between properties of temperament and character and total bilirubin levels. Methods A total of 1665 young male individuals aged from 19 to 30 who were admitted for occupational examinations were included in this study. Careful patient history was taken, a detailed physical examination was conducted, and hematologic and biochemical tests and abdominal ultrasonography were performed. The Turkish version of the Temperament and Character Inventory (TCI) was administered to all participants. 81 patients diagnosed with GS and 150 randomly chosen healthy individuals (control group) were investigated with comparison and correlation analyses. Results GS patients had higher scores than healthy controls for disorderliness (NS4) (p = 0.018), sentimentality (RD1) (p = 0.042), and fatigability (HA4) (p = 0.03). Moreover, Gilbert syndrome patients scored lower than controls for empathy (C2) (p = 0.041) and transpersonal identification (ST2) (p = 0.044). Bilirubin levels were positively associated with disorderliness (NS4) (r = 0.141, p = 0.032) and fatigability (HA4) (r = 0.14, p = 0.033). Conclusions GS patients may have some different personality characteristics from healthy individuals. This study is an initial exploration of the personality structure of GS patients and the findings should be interpreted with caution. Further prospective studies are needed to identify the relationship between Gilbert disease and personality characteristics. |
| first_indexed | 2024-12-17T23:19:13Z |
| format | Article |
| id | doaj.art-1365d257ed534605808aa3d1cb6b7bab |
| institution | Directory Open Access Journal |
| issn | 2238-0019 |
| language | English |
| last_indexed | 2024-12-17T23:19:13Z |
| publishDate | 2021-04-01 |
| publisher | Associação de Psiquiatria do Rio Grande do Sul |
| record_format | Article |
| series | Trends in Psychiatry and Psychotherapy |
| spelling | doaj.art-1365d257ed534605808aa3d1cb6b7bab2022-12-21T21:28:57ZengAssociação de Psiquiatria do Rio Grande do SulTrends in Psychiatry and Psychotherapy2238-00192021-04-0143215115810.47626/2237-6089-2020-0003Associations between Gilbert’s syndrome and personality characteristicsTolga Düzenlihttps://orcid.org/0000-0002-6279-1018Özgür Madenhttps://orcid.org/0000-0002-0430-5747Alpaslan Tanoğluhttps://orcid.org/0000-0002-7477-6640Mustafa Kaplanhttps://orcid.org/0000-0002-0354-4762Yusuf Yazganhttps://orcid.org/0000-0002-8083-0463Abstract Objective Gilbert’s syndrome (GS) is a benign genetic disorder that is characterized by intermittent mild jaundice in which the liver doesn’t process bilirubin properly. The aim of this study was to determine whether GS patients have a different personality structure and if there are associations between properties of temperament and character and total bilirubin levels. Methods A total of 1665 young male individuals aged from 19 to 30 who were admitted for occupational examinations were included in this study. Careful patient history was taken, a detailed physical examination was conducted, and hematologic and biochemical tests and abdominal ultrasonography were performed. The Turkish version of the Temperament and Character Inventory (TCI) was administered to all participants. 81 patients diagnosed with GS and 150 randomly chosen healthy individuals (control group) were investigated with comparison and correlation analyses. Results GS patients had higher scores than healthy controls for disorderliness (NS4) (p = 0.018), sentimentality (RD1) (p = 0.042), and fatigability (HA4) (p = 0.03). Moreover, Gilbert syndrome patients scored lower than controls for empathy (C2) (p = 0.041) and transpersonal identification (ST2) (p = 0.044). Bilirubin levels were positively associated with disorderliness (NS4) (r = 0.141, p = 0.032) and fatigability (HA4) (r = 0.14, p = 0.033). Conclusions GS patients may have some different personality characteristics from healthy individuals. This study is an initial exploration of the personality structure of GS patients and the findings should be interpreted with caution. Further prospective studies are needed to identify the relationship between Gilbert disease and personality characteristics.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892021000200151&tlng=enGilbert’s syndromeTemperament and Character İnventorypersonality profile |
| spellingShingle | Tolga Düzenli Özgür Maden Alpaslan Tanoğlu Mustafa Kaplan Yusuf Yazgan Associations between Gilbert’s syndrome and personality characteristics Trends in Psychiatry and Psychotherapy Gilbert’s syndrome Temperament and Character İnventory personality profile |
| title | Associations between Gilbert’s syndrome and personality characteristics |
| title_full | Associations between Gilbert’s syndrome and personality characteristics |
| title_fullStr | Associations between Gilbert’s syndrome and personality characteristics |
| title_full_unstemmed | Associations between Gilbert’s syndrome and personality characteristics |
| title_short | Associations between Gilbert’s syndrome and personality characteristics |
| title_sort | associations between gilbert s syndrome and personality characteristics |
| topic | Gilbert’s syndrome Temperament and Character İnventory personality profile |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892021000200151&tlng=en |
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