EBF1, PAX5, and MYC: regulation on B cell development and association with hematologic neoplasms

EBF1, PAX5, and MYC: regulation on B cell development and association with hematologic neoplasms

During lymphocyte development, a diverse repertoire of lymphocyte antigen receptors is produced to battle against pathogens, which is the basis of adaptive immunity. The diversity of the lymphocyte antigen receptors arises primarily from recombination-activated gene (RAG) protein-mediated V(D)J rear...

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Bibliographic Details
Main Authors: Li Li, Daiquan Zhang, Xinmei Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
EBF1
PAX5
MYC
V(D)J rearrangement
B cell development
hematologic neoplasms
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1320689/full

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