Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa
Abstract Background vulvar cancer, once predominantly diagnosed in older women, is increasingly being diagnosed in younger individuals, due to Human Papillomavirus (HPV) infection. Our study aimed to describe the epidemiological and histopathological aspects of vulvar cancer in Togo and its associat...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12905-023-02669-6 |
| _version_ | 1797451585145536512 |
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| author | Tchin Darré Bagassam Sama Toukilnan Djiwa Whitney E.D. Afantodji-Agbeti Mayi Bombone Yendoubé Kambote Panakinao Simgban Bingo K M’Bortche Baguilane Douaguibe Koffi Amégbor Mazamaesso Tchaou Abdoul-Samadou Aboubakari Bayaki Saka Gado Napo-Koura |
| author_facet | Tchin Darré Bagassam Sama Toukilnan Djiwa Whitney E.D. Afantodji-Agbeti Mayi Bombone Yendoubé Kambote Panakinao Simgban Bingo K M’Bortche Baguilane Douaguibe Koffi Amégbor Mazamaesso Tchaou Abdoul-Samadou Aboubakari Bayaki Saka Gado Napo-Koura |
| author_sort | Tchin Darré |
| collection | DOAJ |
| description | Abstract Background vulvar cancer, once predominantly diagnosed in older women, is increasingly being diagnosed in younger individuals, due to Human Papillomavirus (HPV) infection. Our study aimed to describe the epidemiological and histopathological aspects of vulvar cancer in Togo and its associated factors. Methods This was a cross-sectional study, conducted on vulvar cancer cases histologically diagnosed at the Pathological Laboratory of Lomé over a period of 17-years (2005–2021). Parameters investigated included age, occupation, risk factors, sample nature, macroscopic tumor aspects, histological types, therapeutic intervenions, and prognostic outcomes. Results A total of 32 cases of vulvar cancer were collected, yieding an annual frequency of 1.88 cases. The average age of the patients was 48±14.12 years with extremes of 27 years and 82 years. Housewives accounted for the largest proportion of cases (37.5%). Among the 32 cases, 27 had identifiable risk factors, with HPV infection being the most prevalentr (33.3%). The ulcero-budding aspect was most frequently observed, and squamous cell carcinoma was the most common histological type, with the majority being well differentiated (89.3%). Statistically significant associations were found between risk factors and histological types, risk factors and degrees of differentiation, as well as between histological types and good differentiation of vulvar cancers. The 3-year survival was estimated at 78.13%. Conclusion The incidence of vulvar cancer is increasing in Togo, particularly among young, primarily due to HPV infection. |
| first_indexed | 2024-03-09T14:56:47Z |
| format | Article |
| id | doaj.art-1367fe7e74ba4c349ac34767c3d215ba |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-03-09T14:56:47Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-1367fe7e74ba4c349ac34767c3d215ba2023-11-26T14:07:17ZengBMCBMC Women's Health1472-68742023-09-012311810.1186/s12905-023-02669-6Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan AfricaTchin Darré0Bagassam Sama1Toukilnan Djiwa2Whitney E.D. Afantodji-Agbeti3Mayi Bombone4Yendoubé Kambote5Panakinao Simgban6Bingo K M’Bortche7Baguilane Douaguibe8Koffi Amégbor9Mazamaesso Tchaou10Abdoul-Samadou Aboubakari11Bayaki Saka12Gado Napo-Koura13Department of Pathology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment Obstetrics and Gynecology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment Obstetrics and Gynecology, University Teaching Hospital of LoméDepartment Obstetrics and Gynecology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméDepartment of Imaging, University Teaching Hospital of Lomé and KaraDepartment Obstetrics and Gynecology, University Teaching Hospital of LoméDepartment of Dermatology, University Teaching Hospital of LoméDepartment of Pathology, University Teaching Hospital of LoméAbstract Background vulvar cancer, once predominantly diagnosed in older women, is increasingly being diagnosed in younger individuals, due to Human Papillomavirus (HPV) infection. Our study aimed to describe the epidemiological and histopathological aspects of vulvar cancer in Togo and its associated factors. Methods This was a cross-sectional study, conducted on vulvar cancer cases histologically diagnosed at the Pathological Laboratory of Lomé over a period of 17-years (2005–2021). Parameters investigated included age, occupation, risk factors, sample nature, macroscopic tumor aspects, histological types, therapeutic intervenions, and prognostic outcomes. Results A total of 32 cases of vulvar cancer were collected, yieding an annual frequency of 1.88 cases. The average age of the patients was 48±14.12 years with extremes of 27 years and 82 years. Housewives accounted for the largest proportion of cases (37.5%). Among the 32 cases, 27 had identifiable risk factors, with HPV infection being the most prevalentr (33.3%). The ulcero-budding aspect was most frequently observed, and squamous cell carcinoma was the most common histological type, with the majority being well differentiated (89.3%). Statistically significant associations were found between risk factors and histological types, risk factors and degrees of differentiation, as well as between histological types and good differentiation of vulvar cancers. The 3-year survival was estimated at 78.13%. Conclusion The incidence of vulvar cancer is increasing in Togo, particularly among young, primarily due to HPV infection.https://doi.org/10.1186/s12905-023-02669-6CancerVulvaHuman papilloma virusSquamous cell carcinomaTogo |
| spellingShingle | Tchin Darré Bagassam Sama Toukilnan Djiwa Whitney E.D. Afantodji-Agbeti Mayi Bombone Yendoubé Kambote Panakinao Simgban Bingo K M’Bortche Baguilane Douaguibe Koffi Amégbor Mazamaesso Tchaou Abdoul-Samadou Aboubakari Bayaki Saka Gado Napo-Koura Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa BMC Women's Health Cancer Vulva Human papilloma virus Squamous cell carcinoma Togo |
| title | Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa |
| title_full | Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa |
| title_fullStr | Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa |
| title_full_unstemmed | Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa |
| title_short | Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa |
| title_sort | factors associated with vulvar cancer from 2005 to 2021 in togo sub saharan africa |
| topic | Cancer Vulva Human papilloma virus Squamous cell carcinoma Togo |
| url | https://doi.org/10.1186/s12905-023-02669-6 |
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