A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma
Abstract A 55-year-old male was admitted to emergency department with a hypoglycemic shock of unknown origin. He was presented with tonic seizure activity after admission. Initial diagnostic procedure could exclude diabetes mellitus, drug side effects, and exogenous insulin application. Detailed eva...
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| Format: | Article |
| Language: | English |
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Kosin University College of Medicine
2014-12-01
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| Series: | Kosin Medical Journal |
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| Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc029-02-09.pdf |
| _version_ | 1811323375130247168 |
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| author | Soo Kyoung Kim Sung Su Kim Bo Ra Kim Jung Hwa Jung Jae Hoon Jung Jong Ryeal Hahm |
| author_facet | Soo Kyoung Kim Sung Su Kim Bo Ra Kim Jung Hwa Jung Jae Hoon Jung Jong Ryeal Hahm |
| author_sort | Soo Kyoung Kim |
| collection | DOAJ |
| description | Abstract A 55-year-old male was admitted to emergency department with a hypoglycemic shock of unknown origin. He was presented with tonic seizure activity after admission. Initial diagnostic procedure could exclude diabetes mellitus, drug side effects, and exogenous insulin application. Detailed evaluation of the patient's history revealed that the patient had experienced repeated hypoglycemic episodes for 2 years. He was diagnosed with hypothyroidism six years ago. Initial laboratory investigations revealed hypoglycemia, hyponatremia, and low plasma cortisol level (0.18 pg/dᄂ)· Sellar magnetic resonance imaging showed empty sella. Replacement therapy with hydrocortisone resulted in the improvement of clinical symptoms. Combined pituitary stimulation test with exception of hypoglycemia induced growth hormone and cortisol stimulation test was performed. The response of thyroid stimulating hormone, prolactin, follicle-stimulating hormone, and luteinizing hormone was normal. We report the case of empty sella syndrome associated with hypoglycemic shock due to with multiple anterior pituitary hormone deficiencies. |
| first_indexed | 2024-04-13T13:54:03Z |
| format | Article |
| id | doaj.art-136bbdfe58254f1fabfee7a7df2de990 |
| institution | Directory Open Access Journal |
| issn | 2005-9531 2586-7024 |
| language | English |
| last_indexed | 2024-04-13T13:54:03Z |
| publishDate | 2014-12-01 |
| publisher | Kosin University College of Medicine |
| record_format | Article |
| series | Kosin Medical Journal |
| spelling | doaj.art-136bbdfe58254f1fabfee7a7df2de9902022-12-22T02:44:16ZengKosin University College of MedicineKosin Medical Journal2005-95312586-70242014-12-0129215115510.7180/kmj.2014.29.2.151142A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic ComaSoo Kyoung Kim0Sung Su Kim1Bo Ra Kim2Jung Hwa Jung3Jae Hoon Jung4Jong Ryeal Hahm5Department of Internal Medicine, Gyeongsang National University, Jinju, KoreaDepartment of Internal Medicine, Gyeongsang National University, Jinju, KoreaDepartment of Internal Medicine, Gyeongsang National University, Jinju, KoreaDepartment of Internal Medicine, Gyeongsang National University, Jinju, KoreaDepartment of Internal Medicine, Gyeongsang National University, Jinju, KoreaDepartment of Internal Medicine, Gyeongsang National University, Jinju, KoreaAbstract A 55-year-old male was admitted to emergency department with a hypoglycemic shock of unknown origin. He was presented with tonic seizure activity after admission. Initial diagnostic procedure could exclude diabetes mellitus, drug side effects, and exogenous insulin application. Detailed evaluation of the patient's history revealed that the patient had experienced repeated hypoglycemic episodes for 2 years. He was diagnosed with hypothyroidism six years ago. Initial laboratory investigations revealed hypoglycemia, hyponatremia, and low plasma cortisol level (0.18 pg/dᄂ)· Sellar magnetic resonance imaging showed empty sella. Replacement therapy with hydrocortisone resulted in the improvement of clinical symptoms. Combined pituitary stimulation test with exception of hypoglycemia induced growth hormone and cortisol stimulation test was performed. The response of thyroid stimulating hormone, prolactin, follicle-stimulating hormone, and luteinizing hormone was normal. We report the case of empty sella syndrome associated with hypoglycemic shock due to with multiple anterior pituitary hormone deficiencies.http://www.kosinmedj.org/upload/pdf/ksmc029-02-09.pdfacth deficiencyempty sellahypoglycemia |
| spellingShingle | Soo Kyoung Kim Sung Su Kim Bo Ra Kim Jung Hwa Jung Jae Hoon Jung Jong Ryeal Hahm A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma Kosin Medical Journal acth deficiency empty sella hypoglycemia |
| title | A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma |
| title_full | A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma |
| title_fullStr | A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma |
| title_full_unstemmed | A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma |
| title_short | A Case with Empty Sella Syndrome Combined with Multiple Anterior Pituitary Hormone Deficiencies Presenting as Hypoglycemic Coma |
| title_sort | case with empty sella syndrome combined with multiple anterior pituitary hormone deficiencies presenting as hypoglycemic coma |
| topic | acth deficiency empty sella hypoglycemia |
| url | http://www.kosinmedj.org/upload/pdf/ksmc029-02-09.pdf |
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