Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages

Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages

Abstract Background Disruption of N6 methyl adenosine (m6A) modulation hampers gene expression and cellular functions, leading to various illnesses. However, the role of m6A modification in osteoarthritis (OA) synovitis remains unclear. This study aimed to explore the expression patterns of m6A regu...

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Bibliographic Details
Main Authors: Yuheng Lu, Hongbo Zhang, Haoyan Pan, Zhicheng Zhang, Hua Zeng, Haoyu Xie, Jianbin Yin, Wen Tang, Rengui Lin, Chun Zeng, Daozhang Cai
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Translational Medicine
Subjects:
m6A regulators
IGF2BP3
Osteoarthritis
Synovial macrophages
Online Access:https://doi.org/10.1186/s12967-023-04173-9

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