Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial.
<h4>Background</h4>Satisfactory treatment is often lacking for spasticity, a highly prevalent motor disorder in patients with spinal cord injury (SCI). Low concentrations of riluzole potently reduce the persistent sodium current, the post-SCI increase in which contributes to spasticity....
Main Authors: | Maëva Cotinat, Isabelle Boquet, Moreno Ursino, Cécile Brocard, Elisabeth Jouve, Corinne Alberti, Laurent Bensoussan, Jean-Michel Viton, Frédéric Brocard, Olivier Blin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0276892 |
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