RPL41, a Small Ribosomal Peptide Deregulated in Tumors, Is Essential for Mitosis and Centrosome Integrity

RPL41, a Small Ribosomal Peptide Deregulated in Tumors, Is Essential for Mitosis and Centrosome Integrity

Ribosomal large subunit protein RPL41 is a basic (positively charged) peptide consisting of only 25 amino acids. An antisense-based functional screening revealed that the down-regulation of RPL41 led to an anchorage-independent growth of NIH3T3 cells in soft agar plates. RPL41 depletion with gene-sp...

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Bibliographic Details
Main Authors:	Shan Wang, Jianmin Huang, Jie He, Aiyuan Wang, Shengqiang Xu, Shiu-Feng Huang, Sheng Xiao
Format:	Article
Language:	English
Published:	Elsevier 2010-03-01
Series:	Neoplasia: An International Journal for Oncology Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558610801071

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