Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?

Coronary artery bypass surgery (CABG) without cardiopulmonary bypass (CPB) may potentially reduce the number of microembolic signals (MES) associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome after surgery. Our aim was to compare the frequenc...

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Main Authors: Malheiros Suzana M. F., Massaro Ayrton R., Gabbai Alberto A., Pessa Clodualdo J. N., Gerola Luis R., Branco João N. R., Lira Filho Edgar B., Christofalo Dejaldo M. J., Federico Darwin, Carvalho Antonio C., Buffolo Enio
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2001-01-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000100002
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author Malheiros Suzana M. F.
Massaro Ayrton R.
Gabbai Alberto A.
Pessa Clodualdo J. N.
Gerola Luis R.
Branco João N. R.
Lira Filho Edgar B.
Christofalo Dejaldo M. J.
Federico Darwin
Carvalho Antonio C.
Buffolo Enio
author_facet Malheiros Suzana M. F.
Massaro Ayrton R.
Gabbai Alberto A.
Pessa Clodualdo J. N.
Gerola Luis R.
Branco João N. R.
Lira Filho Edgar B.
Christofalo Dejaldo M. J.
Federico Darwin
Carvalho Antonio C.
Buffolo Enio
author_sort Malheiros Suzana M. F.
collection DOAJ
description Coronary artery bypass surgery (CABG) without cardiopulmonary bypass (CPB) may potentially reduce the number of microembolic signals (MES) associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome after surgery. Our aim was to compare the frequency of MES and neurologic complications in CABG with and without CPB. Twenty patients eligible to routine CABG without CPB were randomized to surgery with CPB and without CPB and continuously monitored by transcranial Doppler. Neurologic examination was performed in all patients before and after surgery. The two groups were similar with respect to demographics, risk factors, grade of aortic atheromatous disease and number of grafts. The frequency of MES in the nonCPB group was considerably lower than in CPB patients, however, we did not observe any change in the neurologic examination during the early postoperative period. Neurologic complications after CABG may be related to the size and composition of MES rather than to their absolute numbers. A large prospective multicentric randomized trial may help to elucidate this complex issue.
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spelling doaj.art-13777ee6cd9a45ac8f13b02d8654655b2022-12-22T03:58:13ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria0004-282X1678-42272001-01-0159115Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?Malheiros Suzana M. F.Massaro Ayrton R.Gabbai Alberto A.Pessa Clodualdo J. N.Gerola Luis R.Branco João N. R.Lira Filho Edgar B.Christofalo Dejaldo M. J.Federico DarwinCarvalho Antonio C.Buffolo EnioCoronary artery bypass surgery (CABG) without cardiopulmonary bypass (CPB) may potentially reduce the number of microembolic signals (MES) associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome after surgery. Our aim was to compare the frequency of MES and neurologic complications in CABG with and without CPB. Twenty patients eligible to routine CABG without CPB were randomized to surgery with CPB and without CPB and continuously monitored by transcranial Doppler. Neurologic examination was performed in all patients before and after surgery. The two groups were similar with respect to demographics, risk factors, grade of aortic atheromatous disease and number of grafts. The frequency of MES in the nonCPB group was considerably lower than in CPB patients, however, we did not observe any change in the neurologic examination during the early postoperative period. Neurologic complications after CABG may be related to the size and composition of MES rather than to their absolute numbers. A large prospective multicentric randomized trial may help to elucidate this complex issue.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000100002coronary artery bypasstranscranial Dopplerpostoperative complicationscardiopulmonary bypasstreatment outcome
spellingShingle Malheiros Suzana M. F.
Massaro Ayrton R.
Gabbai Alberto A.
Pessa Clodualdo J. N.
Gerola Luis R.
Branco João N. R.
Lira Filho Edgar B.
Christofalo Dejaldo M. J.
Federico Darwin
Carvalho Antonio C.
Buffolo Enio
Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
Arquivos de Neuro-Psiquiatria
coronary artery bypass
transcranial Doppler
postoperative complications
cardiopulmonary bypass
treatment outcome
title Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
title_full Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
title_fullStr Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
title_full_unstemmed Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
title_short Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
title_sort is the number of microembolic signals related to neurologic outcome in coronary bypass surgery
topic coronary artery bypass
transcranial Doppler
postoperative complications
cardiopulmonary bypass
treatment outcome
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000100002
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