Screening and verification of antiviral compounds against HSV-1 using a method based on a plaque inhibition assay

Screening and verification of antiviral compounds against HSV-1 using a method based on a plaque inhibition assay

Abstract Background Herpes simplex virus type 1 (HSV-1) infection is a common viral disease that mainly causes oral lesions, but can also cause genital lesions in some instances. Current treatments with nucleoside analogs are limited by the emergence of drug resistance. Therefore, novel anti-HSV-1 d...

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Bibliographic Details
Main Authors: Yingxian Yin, Jiahui Li, Ling Su, Zhiying Ou, Qingqun Lv, Misi Xiao, Changbing Wang, Dan Zeng, Yiling Gu, Fengxia Yang, Minxia Chen, Shaojuan Feng, Wanming Hu, Fengling Bu, Bing Zhu, Yi Xu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Infectious Diseases
Subjects:
Antiviral drug screening
HSV-1
Plaque formation
Plaque inhibition test
Online Access:https://doi.org/10.1186/s12879-023-08843-3

Internet

https://doi.org/10.1186/s12879-023-08843-3

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