Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults

Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults

Many physiologic differences between children and adults may result in age-related changes in pharmacokinetics and pharmacodynamics. Factors such as gastric pH and emptying time, intestinal transit time, immaturity of secretion and activity of bile and pancreatic fluid among other factors determine...

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Bibliographic Details
Main Authors: Jose T. Ramos, Marta Arteta, Pilar Tejada, Alfredo Hernandez, Raul Perez, Eva Fernandez
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Pharmaceutics
Subjects:
pharmacokinetics
children
neonates
infants
bioavailability
distribution
metabolism
excretion
Online Access:http://www.mdpi.com/1999-4923/3/1/53/

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