Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine?
Abstract Background Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echographic multi-spectrometry (REMS), represents an innovative diagnostic tool...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-022-05430-6 |
| _version_ | 1811250522209910784 |
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| author | Carla Caffarelli Maria Dea Tomai Pitinca Antonella Al Refaie Michela De Vita Simone Catapano Stefano Gonnelli |
| author_facet | Carla Caffarelli Maria Dea Tomai Pitinca Antonella Al Refaie Michela De Vita Simone Catapano Stefano Gonnelli |
| author_sort | Carla Caffarelli |
| collection | DOAJ |
| description | Abstract Background Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echographic multi-spectrometry (REMS), represents an innovative diagnostic tool that seems to be able to investigate bone quality and provide an estimation of fracture risk independent of BMD. The aim of this paper was to evaluate whether the use of REMS technology can favor the diagnosis of osteoporosis in subjects with an apparent increase in BMD. Methods In a cohort of 159 postmenopausal (66.2 ± 11.6 yrs) women with overestimated BMD by DXA at the lumbar spine, we performed an echographic scan with the REMS technique. Results The mean values of BMD at different skeletal sites obtained by the DXA and REMS techniques showed that the BMD T-scores by REMS were significantly lower than those obtained by the DXA technique both at the lumbar spine (p < 0.01) and at all femoral subregions (p < 0.05). In OA subjects, the percentage of women classified as “osteoporotic” on the basis of BMD by REMS was markedly higher with respect to those classified by DXA (35.1% vs 9.3%, respectively). Similarly, the REMS allows a greater number of fractured patients to be classified as osteoporotic than DXA (58.7% vs 23.3%, respectively). Conclusions REMS technology by the analysis of native raw unfiltered ultrasound signals appears to be able to overcome the most common artifacts, such as OA and vertebral fracture of the lumbar spine, which affect the value of BMD by DXA. |
| first_indexed | 2024-04-12T16:04:59Z |
| format | Article |
| id | doaj.art-137f605b3d764ee4911dfb62eb2a1580 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-04-12T16:04:59Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-137f605b3d764ee4911dfb62eb2a15802022-12-22T03:26:04ZengBMCBMC Musculoskeletal Disorders1471-24742022-05-012311810.1186/s12891-022-05430-6Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine?Carla Caffarelli0Maria Dea Tomai Pitinca1Antonella Al Refaie2Michela De Vita3Simone Catapano4Stefano Gonnelli5Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteDepartment of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteDepartment of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteDepartment of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteDepartment of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteDepartment of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le ScotteAbstract Background Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echographic multi-spectrometry (REMS), represents an innovative diagnostic tool that seems to be able to investigate bone quality and provide an estimation of fracture risk independent of BMD. The aim of this paper was to evaluate whether the use of REMS technology can favor the diagnosis of osteoporosis in subjects with an apparent increase in BMD. Methods In a cohort of 159 postmenopausal (66.2 ± 11.6 yrs) women with overestimated BMD by DXA at the lumbar spine, we performed an echographic scan with the REMS technique. Results The mean values of BMD at different skeletal sites obtained by the DXA and REMS techniques showed that the BMD T-scores by REMS were significantly lower than those obtained by the DXA technique both at the lumbar spine (p < 0.01) and at all femoral subregions (p < 0.05). In OA subjects, the percentage of women classified as “osteoporotic” on the basis of BMD by REMS was markedly higher with respect to those classified by DXA (35.1% vs 9.3%, respectively). Similarly, the REMS allows a greater number of fractured patients to be classified as osteoporotic than DXA (58.7% vs 23.3%, respectively). Conclusions REMS technology by the analysis of native raw unfiltered ultrasound signals appears to be able to overcome the most common artifacts, such as OA and vertebral fracture of the lumbar spine, which affect the value of BMD by DXA.https://doi.org/10.1186/s12891-022-05430-6OsteoporosisOsteoarthritisVertebral fracturesRadiofrequency echographic multi-spectrometry (REMS)Dual-energy X-ray absorptiometry (DXA) |
| spellingShingle | Carla Caffarelli Maria Dea Tomai Pitinca Antonella Al Refaie Michela De Vita Simone Catapano Stefano Gonnelli Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? BMC Musculoskeletal Disorders Osteoporosis Osteoarthritis Vertebral fractures Radiofrequency echographic multi-spectrometry (REMS) Dual-energy X-ray absorptiometry (DXA) |
| title | Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? |
| title_full | Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? |
| title_fullStr | Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? |
| title_full_unstemmed | Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? |
| title_short | Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine? |
| title_sort | could radiofrequency echographic multispectrometry rems overcome the overestimation in bmd by dual energy x ray absorptiometry dxa at the lumbar spine |
| topic | Osteoporosis Osteoarthritis Vertebral fractures Radiofrequency echographic multi-spectrometry (REMS) Dual-energy X-ray absorptiometry (DXA) |
| url | https://doi.org/10.1186/s12891-022-05430-6 |
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