Diminished CD103 (aEb7) Expression on Resident T cells from the Female Genital Tract of HIV-positive women

Diminished CD103 (aEb7) Expression on Resident T cells from the Female Genital Tract of HIV-positive women

Background:Tissue resident memory T cells (TrM) provide an enhanced response against infection at mucosal surfaces, yet their function has not been extensively studied in humans, including the female genital tract (FGT). Methods: Using polychromatic flow cytometry, we studied TrM cells, defined as...

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Bibliographic Details
Main Authors: David C. Moylan, Paul A. Goepfert, Mirjam-Colette Kempf, Michael S. Saag, Holly E. Richter, Jiri Mestecky, Steffanie Sabbaj
Format: Article
Language:English
Published: Case Western Reserve University 2017-01-01
Series:Pathogens and Immunity
Subjects:
Tissue Resident Memory T cells
female genital tract
HIV-1
CD103
mucosal immunity
CD8+ T cells
CD4 T cells
Online Access:https://paijournal.com/index.php/paijournal/article/view/166

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