INTRA-ERYTHROCYTE INVASION OF ESCHERICHIA COLI STRAINS WITH VARIOUS LEVELS OF ANTIHEMOGLOBIN ACTIVITY IN EXPERIMENT
Aim. Study of intra-erythrocyte invasion of Escherichia coli strains with various levels of antihemoglobin activity on a model of generalized infection. Materials and methods. Experiments were carried out on 72 male mice. Generalized infection was induced by intravenous administration of E.coli stra...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Central Research Institute for Epidemiology
2015-08-01
|
| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.crie.ru/jour/article/view/14071 |
| Summary: | Aim. Study of intra-erythrocyte invasion of Escherichia coli strains with various levels of antihemoglobin activity on a model of generalized infection. Materials and methods. Experiments were carried out on 72 male mice. Generalized infection was induced by intravenous administration of E.coli strain day culture suspension with various values of hemolytic and antihemoglobin activity. The levels of hemoglobin in animal blood was determined by hemoglobin-cyanide method. Intra-erythrocyte invasion of E.coli was studied by using laser scanning confocal microscopy (LSCM). Results. The largest decline (p |
|---|---|
| ISSN: | 0372-9311 2686-7613 |