Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis
We report a case of a human leukocyte antigen B27 (HLA-B27)-negative patient with cystoid macular edema (CME) and ankylosing spondylitis (AS) after treatment with triamcinolone acetonide. The patient complained of deterioration of visual acuity of the right eye during the last 10 days. At presentati...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2010-12-01
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| Series: | Case Reports in Ophthalmology |
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| Online Access: | http://www.karger.com/Article/FullText/322913 |
| _version_ | 1818925752083546112 |
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| author | M.M. Moschos Z. Gatzioufas I. Margetis |
| author_facet | M.M. Moschos Z. Gatzioufas I. Margetis |
| author_sort | M.M. Moschos |
| collection | DOAJ |
| description | We report a case of a human leukocyte antigen B27 (HLA-B27)-negative patient with cystoid macular edema (CME) and ankylosing spondylitis (AS) after treatment with triamcinolone acetonide. The patient complained of deterioration of visual acuity of the right eye during the last 10 days. At presentation visual acuity of the right eye was 0.2, and the ophthalmic examination did not reveal any sign of active uveitis. Fluorescein angiography (FA) and ocular coherent tomography (OCT) showed CME. The left eye was normal with a visual acuity of 0.9. Eight weeks after intravitreal injection of triamcinolone acetonide, visual acuity improved to 0.8 and OCT revealed regression of macular edema. Six months later no recurrence was observed. Our case report indicates for the first time that CME may occur in AS independently of the presence of HLA-B27 and intraocular inflammation. Intravitreal use of triamcinolone acetonide can reduce macular edema and restore visual acuity. |
| first_indexed | 2024-12-20T02:46:13Z |
| format | Article |
| id | doaj.art-138ca28cebbe44a9b8d1a518cfb88ebf |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-12-20T02:46:13Z |
| publishDate | 2010-12-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-138ca28cebbe44a9b8d1a518cfb88ebf2022-12-21T19:56:10ZengKarger PublishersCase Reports in Ophthalmology1663-26992010-12-011210510910.1159/000322913322913Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing SpondylitisM.M. MoschosZ. GatzioufasI. MargetisWe report a case of a human leukocyte antigen B27 (HLA-B27)-negative patient with cystoid macular edema (CME) and ankylosing spondylitis (AS) after treatment with triamcinolone acetonide. The patient complained of deterioration of visual acuity of the right eye during the last 10 days. At presentation visual acuity of the right eye was 0.2, and the ophthalmic examination did not reveal any sign of active uveitis. Fluorescein angiography (FA) and ocular coherent tomography (OCT) showed CME. The left eye was normal with a visual acuity of 0.9. Eight weeks after intravitreal injection of triamcinolone acetonide, visual acuity improved to 0.8 and OCT revealed regression of macular edema. Six months later no recurrence was observed. Our case report indicates for the first time that CME may occur in AS independently of the presence of HLA-B27 and intraocular inflammation. Intravitreal use of triamcinolone acetonide can reduce macular edema and restore visual acuity.http://www.karger.com/Article/FullText/322913Ankylosing spondylitisUveitisTriamcinolone acetonide |
| spellingShingle | M.M. Moschos Z. Gatzioufas I. Margetis Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis Case Reports in Ophthalmology Ankylosing spondylitis Uveitis Triamcinolone acetonide |
| title | Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis |
| title_full | Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis |
| title_fullStr | Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis |
| title_full_unstemmed | Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis |
| title_short | Intravitreal Triamcinolone Acetonide for Macular Edema in HLA-B27 Negative Ankylosing Spondylitis |
| title_sort | intravitreal triamcinolone acetonide for macular edema in hla b27 negative ankylosing spondylitis |
| topic | Ankylosing spondylitis Uveitis Triamcinolone acetonide |
| url | http://www.karger.com/Article/FullText/322913 |
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