Foveal evaluation in diabetic patients with macular edema using optical coherence tomography angiography
Purpose The aim of this study was to evaluate the foveal avascular zone (FAZ) in patients with diabetic macular edema (DME) by documenting the morphological and quantitative changes by optical coherence tomography angiography (OCTA). Patients and methods The study included 47 eyes of 47 participants...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Delta Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.djo.eg.net/article.asp?issn=1110-9173;year=2020;volume=21;issue=1;spage=43;epage=48;aulast=Gadallah |
| Summary: | Purpose The aim of this study was to evaluate the foveal avascular zone (FAZ) in patients with diabetic macular edema (DME) by documenting the morphological and quantitative changes by optical coherence tomography angiography (OCTA).
Patients and methods The study included 47 eyes of 47 participants. They were allocated into two groups: 27 eyes of 27 patients having DME and 20 eyes of 20 age-matched healthy controls. All study participants were imaged using OCTA machine to assess the FAZ area and to compare the changes between patients and controls.
Results The FAZ area was significantly enlarged in patients with DME than in controls (P<0.001), together with the presence of other morphological changes (microaneurysms, capillary loops, and widened intercapillary spaces). Retinal vessel densities were also reduced in patients than in controls at both the superficial and deep retinal capillary complexes.
Conclusion Qualitative and quantitative changes do occur in patients with DME, which could be documented using the OCTA. This helps better disease staging and monitoring as well as treatment decisions. |
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| ISSN: | 1110-9173 2090-4835 |