Lipid Aberrations in Lichen Planus

Lichen planus (LP) is a dermatosis without a fully understood etiopathogenesis, the frequency of which is estimated to be less than 1% among the population. LP may involve the glabrous skin, mucosal membranes, scalp, nails and genital area. Nowadays, there are reports of its association with lipid h...

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Main Authors: Julia Nowowiejska, Anna Baran, Iwona Flisiak
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/11/1008
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author Julia Nowowiejska
Anna Baran
Iwona Flisiak
author_facet Julia Nowowiejska
Anna Baran
Iwona Flisiak
author_sort Julia Nowowiejska
collection DOAJ
description Lichen planus (LP) is a dermatosis without a fully understood etiopathogenesis, the frequency of which is estimated to be less than 1% among the population. LP may involve the glabrous skin, mucosal membranes, scalp, nails and genital area. Nowadays, there are reports of its association with lipid homeostasis aberrations. In this review, we present the contemporary view of this matter. Dyslipidemia, especially hypertriglyceridemia, seems to be an actual problem in this group of patients, and along with abnormal arterial vessel parameters, indicates an increased risk of atherosclerosis in these subjects. Dermatologists should be attentive to this relationship and aware that the patients may develop different metabolic complications. More studies are required to establish clear guidelines on the management of lipid aberrations in lichen planus.
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spelling doaj.art-138f4c87f8564013b68c6e0a8000b78f2023-11-24T05:49:33ZengMDPI AGMetabolites2218-19892022-10-011211100810.3390/metabo12111008Lipid Aberrations in Lichen PlanusJulia Nowowiejska0Anna Baran1Iwona Flisiak2Department of Dermatology and Venereology, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Dermatology and Venereology, Medical University of Bialystok, 15-540 Bialystok, PolandLichen planus (LP) is a dermatosis without a fully understood etiopathogenesis, the frequency of which is estimated to be less than 1% among the population. LP may involve the glabrous skin, mucosal membranes, scalp, nails and genital area. Nowadays, there are reports of its association with lipid homeostasis aberrations. In this review, we present the contemporary view of this matter. Dyslipidemia, especially hypertriglyceridemia, seems to be an actual problem in this group of patients, and along with abnormal arterial vessel parameters, indicates an increased risk of atherosclerosis in these subjects. Dermatologists should be attentive to this relationship and aware that the patients may develop different metabolic complications. More studies are required to establish clear guidelines on the management of lipid aberrations in lichen planus.https://www.mdpi.com/2218-1989/12/11/1008lichen planusmetabolic syndromelipidslipid aberrationsatherosclerosisstatins
spellingShingle Julia Nowowiejska
Anna Baran
Iwona Flisiak
Lipid Aberrations in Lichen Planus
Metabolites
lichen planus
metabolic syndrome
lipids
lipid aberrations
atherosclerosis
statins
title Lipid Aberrations in Lichen Planus
title_full Lipid Aberrations in Lichen Planus
title_fullStr Lipid Aberrations in Lichen Planus
title_full_unstemmed Lipid Aberrations in Lichen Planus
title_short Lipid Aberrations in Lichen Planus
title_sort lipid aberrations in lichen planus
topic lichen planus
metabolic syndrome
lipids
lipid aberrations
atherosclerosis
statins
url https://www.mdpi.com/2218-1989/12/11/1008
work_keys_str_mv AT julianowowiejska lipidaberrationsinlichenplanus
AT annabaran lipidaberrationsinlichenplanus
AT iwonaflisiak lipidaberrationsinlichenplanus