Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects
Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014-12-01
|
| Series: | Entropy |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1099-4300/16/12/6384 |
| _version_ | 1811303173538709504 |
|---|---|
| author | Mathias Baumert Barbora Czippelova Anand Ganesan Martin Schmidt Sebastian Zaunseder Michal Javorka |
| author_facet | Mathias Baumert Barbora Czippelova Anand Ganesan Martin Schmidt Sebastian Zaunseder Michal Javorka |
| author_sort | Mathias Baumert |
| collection | DOAJ |
| description | Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects during an experimental protocol that involved head-up tilt and mental arithmetic stress and computed sample entropy, cross-sample entropy and causal interactions based on conditional entropy from RR and QT interval time series. Head-up tilt resulted in a significant reduction in sample entropy of RR intervals and cross-sample entropy, while mental arithmetic stress resulted in a significant reduction in coupling directed from RR to QT. In conclusion, measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarisation variability from heart rate variability elicited by orthostatic or mental arithmetic stress. |
| first_indexed | 2024-04-13T07:42:05Z |
| format | Article |
| id | doaj.art-1391acb1476a4362bc2f162701e7db3a |
| institution | Directory Open Access Journal |
| issn | 1099-4300 |
| language | English |
| last_indexed | 2024-04-13T07:42:05Z |
| publishDate | 2014-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Entropy |
| spelling | doaj.art-1391acb1476a4362bc2f162701e7db3a2022-12-22T02:55:50ZengMDPI AGEntropy1099-43002014-12-0116126384639310.3390/e16126384e16126384Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy SubjectsMathias Baumert0Barbora Czippelova1Anand Ganesan2Martin Schmidt3Sebastian Zaunseder4Michal Javorka5School of Electrical and Electronic Engineering, University of Adelaide, Adelaide SA 5005, AustraliaDepartment of Physiology, Jessenius Faculty of Medicine, Comenius University, Mala Hora 4, Martin 036 01, SlovakiaSchool of Medicine, University of Adelaide, Adelaide SA 5005, AustraliaInstitute of Biomedical Engineering, Technical University Dresden, Dresden 01069, GermanyInstitute of Biomedical Engineering, Technical University Dresden, Dresden 01069, GermanyDepartment of Physiology, Jessenius Faculty of Medicine, Comenius University, Mala Hora 4, Martin 036 01, SlovakiaAutonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects during an experimental protocol that involved head-up tilt and mental arithmetic stress and computed sample entropy, cross-sample entropy and causal interactions based on conditional entropy from RR and QT interval time series. Head-up tilt resulted in a significant reduction in sample entropy of RR intervals and cross-sample entropy, while mental arithmetic stress resulted in a significant reduction in coupling directed from RR to QT. In conclusion, measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarisation variability from heart rate variability elicited by orthostatic or mental arithmetic stress.http://www.mdpi.com/1099-4300/16/12/6384QT variabilityheart rate variabilitystresssympatheticcomplexity |
| spellingShingle | Mathias Baumert Barbora Czippelova Anand Ganesan Martin Schmidt Sebastian Zaunseder Michal Javorka Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects Entropy QT variability heart rate variability stress sympathetic complexity |
| title | Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects |
| title_full | Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects |
| title_fullStr | Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects |
| title_full_unstemmed | Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects |
| title_short | Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects |
| title_sort | entropy analysis of rr and qt interval variability during orthostatic and mental stress in healthy subjects |
| topic | QT variability heart rate variability stress sympathetic complexity |
| url | http://www.mdpi.com/1099-4300/16/12/6384 |
| work_keys_str_mv | AT mathiasbaumert entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects AT barboraczippelova entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects AT anandganesan entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects AT martinschmidt entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects AT sebastianzaunseder entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects AT michaljavorka entropyanalysisofrrandqtintervalvariabilityduringorthostaticandmentalstressinhealthysubjects |