Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy

Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy

The mucosal barrier remains a major barrier in the pulmonary drug delivery system, as mucociliary clearance in the airway accelerates the removal of inhaled nanoparticles (NPs). Herein, we designed and developed the inhalable Pluronic F127-modified silk fibroin NPs loading with quercetin (marked as...

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Bibliographic Details
Main Authors: Yu Tang, Lanfang Zhang, Rui Sun, Baiyi Luo, Yu Zhou, Yan Zhang, Yuqi Liang, Bo Xiao, Chenhui Wang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Pulmonary drug delivery
Mucus penetration
Quercetin
Pluronic F127
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087623000600

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