Study of Lithium Biodistribution and Nephrotoxicity in Skin Melanoma Mice Model: The First Step towards Implementing Lithium Neutron Capture Therapy

Study of Lithium Biodistribution and Nephrotoxicity in Skin Melanoma Mice Model: The First Step towards Implementing Lithium Neutron Capture Therapy

Boron neutron capture therapy (BNCT) is one of the promising treatment methods for malignant melanoma. The main issue of this technology is the insufficient selectivity of <sup>10</sup>B accumulation in tumor cells. As a result of the neutron absorption by boron, an 84% energy release oc...

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Bibliographic Details
Main Authors: Iuliia Taskaeva, Anna Kasatova, Dmitry Surodin, Nataliya Bgatova, Sergey Taskaev
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Life
Subjects:
skin melanoma
lithium carbonate
kidney
toxicity
lithium neutron capture therapy
Online Access:https://www.mdpi.com/2075-1729/13/2/518

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