Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan

Background: Colorectal cancer is a common type of cancer worldwide, including in Sudan. However, few studies have assessed its demographic, clinical and pathological patterns in the Sudanese population. Objective: To assess the demographic, clinical and pathological patterns in patients with colorec...

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Main Authors: Husam S Khougali, Ahmed A Albashir, Hatoun N Daffaalla, Mohammed Salih
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Saudi Journal of Medicine and Medical Sciences
Subjects:
Online Access:http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=146;epage=150;aulast=Khougali
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author Husam S Khougali
Ahmed A Albashir
Hatoun N Daffaalla
Mohammed Salih
author_facet Husam S Khougali
Ahmed A Albashir
Hatoun N Daffaalla
Mohammed Salih
author_sort Husam S Khougali
collection DOAJ
description Background: Colorectal cancer is a common type of cancer worldwide, including in Sudan. However, few studies have assessed its demographic, clinical and pathological patterns in the Sudanese population. Objective: To assess the demographic, clinical and pathological patterns in patients with colorectal cancer at National Cancer Institute, University of Gezira, Sudan. Methods: This retrospective, cross-sectional study analyzed the data of all colorectal cancer patients who presented to National Cancer Institute, University of Gezira, between January 2016 and December 2017. National Cancer Institute, University of Gezira, is one of the two National Cancer Institutes in Sudan and receives patients from across Sudan. The demographic, clinical and pathological information were extracted from the patients' files. Results: A total of 163 colorectal cancer patients who presented to National Cancer Institute during the study period and met the inclusion criteria were included in this study. Most patients were aged >40–69 years (58.8%), were male (53.4%) and from Central Sudan (65.6%). About 44% of the patients were diagnosed 6–12 months from the disease onset and 26.8% after >12 months. Change in bowel habits (51.5%), rectal bleeding (42.3%) and abdominal pain (32.5%) were the most common clinical presentations. About 58% of the patients did not undergo per rectal examination during their initial presentation. Rectum was the most common site of tumor (58.9%), and the majority of patients had Grade I adenocarcinoma (50.3%). Duke's Class B (38%) and Class C (31%) were the most common stages of the patients' tumor, and signet ring carcinoma was found in 4.9% of the patients. Conclusion: This study found that in Sudan, colorectal cancer patients most commonly present late after the onset of symptoms, with an advanced stage and aggressive pattern as well as the proportion of younger patients is high. Further, per rectal examination is often not performed during the initial presentation.
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spelling doaj.art-1397dfb2055e4bb0bb4926676eda62552022-12-22T01:42:19ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2019-01-017314615010.4103/sjmms.sjmms_138_18Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, SudanHusam S KhougaliAhmed A AlbashirHatoun N DaffaallaMohammed SalihBackground: Colorectal cancer is a common type of cancer worldwide, including in Sudan. However, few studies have assessed its demographic, clinical and pathological patterns in the Sudanese population. Objective: To assess the demographic, clinical and pathological patterns in patients with colorectal cancer at National Cancer Institute, University of Gezira, Sudan. Methods: This retrospective, cross-sectional study analyzed the data of all colorectal cancer patients who presented to National Cancer Institute, University of Gezira, between January 2016 and December 2017. National Cancer Institute, University of Gezira, is one of the two National Cancer Institutes in Sudan and receives patients from across Sudan. The demographic, clinical and pathological information were extracted from the patients' files. Results: A total of 163 colorectal cancer patients who presented to National Cancer Institute during the study period and met the inclusion criteria were included in this study. Most patients were aged >40–69 years (58.8%), were male (53.4%) and from Central Sudan (65.6%). About 44% of the patients were diagnosed 6–12 months from the disease onset and 26.8% after >12 months. Change in bowel habits (51.5%), rectal bleeding (42.3%) and abdominal pain (32.5%) were the most common clinical presentations. About 58% of the patients did not undergo per rectal examination during their initial presentation. Rectum was the most common site of tumor (58.9%), and the majority of patients had Grade I adenocarcinoma (50.3%). Duke's Class B (38%) and Class C (31%) were the most common stages of the patients' tumor, and signet ring carcinoma was found in 4.9% of the patients. Conclusion: This study found that in Sudan, colorectal cancer patients most commonly present late after the onset of symptoms, with an advanced stage and aggressive pattern as well as the proportion of younger patients is high. Further, per rectal examination is often not performed during the initial presentation.http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=146;epage=150;aulast=KhougaliClinicopathologicalcolorectal cancerdemographicGezirapresentationSudan
spellingShingle Husam S Khougali
Ahmed A Albashir
Hatoun N Daffaalla
Mohammed Salih
Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
Saudi Journal of Medicine and Medical Sciences
Clinicopathological
colorectal cancer
demographic
Gezira
presentation
Sudan
title Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
title_full Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
title_fullStr Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
title_full_unstemmed Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
title_short Demographic and clinicopathological patterns of colorectal cancer at the National Cancer Institute, Sudan
title_sort demographic and clinicopathological patterns of colorectal cancer at the national cancer institute sudan
topic Clinicopathological
colorectal cancer
demographic
Gezira
presentation
Sudan
url http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=146;epage=150;aulast=Khougali
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AT ahmedaalbashir demographicandclinicopathologicalpatternsofcolorectalcanceratthenationalcancerinstitutesudan
AT hatounndaffaalla demographicandclinicopathologicalpatternsofcolorectalcanceratthenationalcancerinstitutesudan
AT mohammedsalih demographicandclinicopathologicalpatternsofcolorectalcanceratthenationalcancerinstitutesudan