Synthetic materials in craniofacial regenerative medicine: A comprehensive overview
The state-of-the-art approach to regenerating different tissues and organs is tissue engineering which includes the three parts of stem cells (SCs), scaffolds, and growth factors. Cellular behaviors such as propagation, differentiation, and assembling the extracellular matrix (ECM) are influenced by...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.987195/full |
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| author | Mohsen Yazdanian Mostafa Alam Kamyar Abbasi Mahdi Rahbar Amin Farjood Elahe Tahmasebi Hamid Tebyaniyan Reza Ranjbar Arian Hesam Arefi |
| author_facet | Mohsen Yazdanian Mostafa Alam Kamyar Abbasi Mahdi Rahbar Amin Farjood Elahe Tahmasebi Hamid Tebyaniyan Reza Ranjbar Arian Hesam Arefi |
| author_sort | Mohsen Yazdanian |
| collection | DOAJ |
| description | The state-of-the-art approach to regenerating different tissues and organs is tissue engineering which includes the three parts of stem cells (SCs), scaffolds, and growth factors. Cellular behaviors such as propagation, differentiation, and assembling the extracellular matrix (ECM) are influenced by the cell’s microenvironment. Imitating the cell’s natural environment, such as scaffolds, is vital to create appropriate tissue. Craniofacial tissue engineering refers to regenerating tissues found in the brain and the face parts such as bone, muscle, and artery. More biocompatible and biodegradable scaffolds are more commensurate with tissue remodeling and more appropriate for cell culture, signaling, and adhesion. Synthetic materials play significant roles and have become more prevalent in medical applications. They have also been used in different forms for producing a microenvironment as ECM for cells. Synthetic scaffolds may be comprised of polymers, bioceramics, or hybrids of natural/synthetic materials. Synthetic scaffolds have produced ECM-like materials that can properly mimic and regulate the tissue microenvironment’s physical, mechanical, chemical, and biological properties, manage adherence of biomolecules and adjust the material’s degradability. The present review article is focused on synthetic materials used in craniofacial tissue engineering in recent decades. |
| first_indexed | 2024-04-12T10:43:13Z |
| format | Article |
| id | doaj.art-1399eddc1ca7417f95400031146f9a23 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-12T10:43:13Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-1399eddc1ca7417f95400031146f9a232022-12-22T03:36:31ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-11-011010.3389/fbioe.2022.987195987195Synthetic materials in craniofacial regenerative medicine: A comprehensive overviewMohsen Yazdanian0Mostafa Alam1Kamyar Abbasi2Mahdi Rahbar3Amin Farjood4Elahe Tahmasebi5Hamid Tebyaniyan6Reza Ranjbar7Arian Hesam Arefi8Research Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Prosthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Restorative Dentistry, School of Dentistry, Ardabil University of Medical Sciences, Ardabil, IranOrthodontic Department, Dental School, Bushehr University of Medical Sciences, Bushehr, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Science and Research, Islimic Azade University, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, IranDental Research Center, Zahedan University of Medical Sciences, Zahedan, IranThe state-of-the-art approach to regenerating different tissues and organs is tissue engineering which includes the three parts of stem cells (SCs), scaffolds, and growth factors. Cellular behaviors such as propagation, differentiation, and assembling the extracellular matrix (ECM) are influenced by the cell’s microenvironment. Imitating the cell’s natural environment, such as scaffolds, is vital to create appropriate tissue. Craniofacial tissue engineering refers to regenerating tissues found in the brain and the face parts such as bone, muscle, and artery. More biocompatible and biodegradable scaffolds are more commensurate with tissue remodeling and more appropriate for cell culture, signaling, and adhesion. Synthetic materials play significant roles and have become more prevalent in medical applications. They have also been used in different forms for producing a microenvironment as ECM for cells. Synthetic scaffolds may be comprised of polymers, bioceramics, or hybrids of natural/synthetic materials. Synthetic scaffolds have produced ECM-like materials that can properly mimic and regulate the tissue microenvironment’s physical, mechanical, chemical, and biological properties, manage adherence of biomolecules and adjust the material’s degradability. The present review article is focused on synthetic materials used in craniofacial tissue engineering in recent decades.https://www.frontiersin.org/articles/10.3389/fbioe.2022.987195/fullsynthetic materialsbiocompatible materialscraniofacial regenerationdentaltissue engineering |
| spellingShingle | Mohsen Yazdanian Mostafa Alam Kamyar Abbasi Mahdi Rahbar Amin Farjood Elahe Tahmasebi Hamid Tebyaniyan Reza Ranjbar Arian Hesam Arefi Synthetic materials in craniofacial regenerative medicine: A comprehensive overview Frontiers in Bioengineering and Biotechnology synthetic materials biocompatible materials craniofacial regeneration dental tissue engineering |
| title | Synthetic materials in craniofacial regenerative medicine: A comprehensive overview |
| title_full | Synthetic materials in craniofacial regenerative medicine: A comprehensive overview |
| title_fullStr | Synthetic materials in craniofacial regenerative medicine: A comprehensive overview |
| title_full_unstemmed | Synthetic materials in craniofacial regenerative medicine: A comprehensive overview |
| title_short | Synthetic materials in craniofacial regenerative medicine: A comprehensive overview |
| title_sort | synthetic materials in craniofacial regenerative medicine a comprehensive overview |
| topic | synthetic materials biocompatible materials craniofacial regeneration dental tissue engineering |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.987195/full |
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