Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates
Although the overall prognosis of differentiated thyroid cancer (DTC), the most common endocrine malignancy, is favorable, a subset of patients exhibits aggressive features. Therefore, preclinical models that can be utilized to investigate DTC pathogenesis and novel treatments are necessary. Various...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/13/11138 |
| _version_ | 1797591461679595520 |
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| author | Hye Ryeon Choi Kwangsoon Kim |
| author_facet | Hye Ryeon Choi Kwangsoon Kim |
| author_sort | Hye Ryeon Choi |
| collection | DOAJ |
| description | Although the overall prognosis of differentiated thyroid cancer (DTC), the most common endocrine malignancy, is favorable, a subset of patients exhibits aggressive features. Therefore, preclinical models that can be utilized to investigate DTC pathogenesis and novel treatments are necessary. Various mouse models have been developed based on advances in thyroid cancer genetics. This review focuses on recent progress in mouse models that have been developed to elucidate the molecular pathogenesis of DTC. |
| first_indexed | 2024-03-11T01:37:46Z |
| format | Article |
| id | doaj.art-139ad0a9525a4dc8ad6796f1b9fb444c |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T01:37:46Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-139ad0a9525a4dc8ad6796f1b9fb444c2023-11-18T16:48:41ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-07-0124131113810.3390/ijms241311138Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent UpdatesHye Ryeon Choi0Kwangsoon Kim1Department of Surgery, Eulji Medical Center, Eulji University School of Medicine, Seoul 01830, Republic of KoreaDepartment of Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of KoreaAlthough the overall prognosis of differentiated thyroid cancer (DTC), the most common endocrine malignancy, is favorable, a subset of patients exhibits aggressive features. Therefore, preclinical models that can be utilized to investigate DTC pathogenesis and novel treatments are necessary. Various mouse models have been developed based on advances in thyroid cancer genetics. This review focuses on recent progress in mouse models that have been developed to elucidate the molecular pathogenesis of DTC.https://www.mdpi.com/1422-0067/24/13/11138thyroid cancerpapillaryfolliculardifferentiatedmouse modelpathogenesis |
| spellingShingle | Hye Ryeon Choi Kwangsoon Kim Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates International Journal of Molecular Sciences thyroid cancer papillary follicular differentiated mouse model pathogenesis |
| title | Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates |
| title_full | Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates |
| title_fullStr | Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates |
| title_full_unstemmed | Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates |
| title_short | Mouse Models to Examine Differentiated Thyroid Cancer Pathogenesis: Recent Updates |
| title_sort | mouse models to examine differentiated thyroid cancer pathogenesis recent updates |
| topic | thyroid cancer papillary follicular differentiated mouse model pathogenesis |
| url | https://www.mdpi.com/1422-0067/24/13/11138 |
| work_keys_str_mv | AT hyeryeonchoi mousemodelstoexaminedifferentiatedthyroidcancerpathogenesisrecentupdates AT kwangsoonkim mousemodelstoexaminedifferentiatedthyroidcancerpathogenesisrecentupdates |