Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease

Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease

Abstract Aggregated alpha-synuclein (α-syn) is a principal constituent of Lewy bodies (LBs) and glial cytoplasmic inclusions (GCIs) observed respectively inside neurons in Parkinson’s disease (PD) and oligodendrocytes in multiple system atrophy (MSA). Yet, the cellular origin, the pathophysiological...

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Bibliographic Details
Main Authors:	Florent Laferrière, Stéphane Claverol, Erwan Bezard, Francesca De Giorgi, François Ichas
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-01-01
Series:	npj Parkinson's Disease
Online Access:	https://doi.org/10.1038/s41531-021-00264-w

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