Antiproliferative effect of mifepristone (RU486) on human neuroblastoma cells (SK-N-SH): in vitro and in vivo studies

Antiproliferative effect of mifepristone (RU486) on human neuroblastoma cells (SK-N-SH): in vitro and in vivo studies

RU486 (mifepristone), a glucocorticoid and progesterone receptor antagonist, has been reported to exert antiproliferative effects on tumor cells. Experiments were performed to analyze the effects of RU486 on the proliferation of the human neuroblastoma, both in vitro and in vivo, using the human neu...

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Bibliographic Details
Main Authors: L.A. Casulari, D. Dondi, G. Pratesi, F. Piva, M. Milani, M. Piccolella, R. Maggi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2020-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Mifepristone
RU486
Cell proliferation
Neuroblastoma
Nude mice
Tumor cell growth
Online Access:http://www.scielo.br/pdf/bjmbr/v53n11/1414-431X-bjmbr-53-11-e10067.pdf

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