In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper

In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper

Piplartine {5,6-dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)pyridinone} and piperine {1-5-(1,3)-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine} are alkaloid amides isolated from Piper. Both have been reported to show cytotoxic activity towards several tumor cell lines. In the pr...

Full description

Bibliographic Details
Main Authors: D.P. Bezerra, F.O. Castro, A.P.N.N. Alves, C. Pessoa, M.O. Moraes, E.R. Silveira, M.A.S. Lima, F.J.M. Elmiro, L.V. Costa-Lotufo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Piplartine
Piperine
Antitumor activity
Toxicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600014

Similar Items

Similar Items