Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation
Over the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of physiological closed-loop control systems (PCLCs). Today, m...
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| Format: | Article |
| Language: | English |
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IEEE
2020-01-01
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| Series: | IEEE Access |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/8964302/ |
| _version_ | 1818935343906291712 |
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| author | Mohammad Javad Khodaei Nicholas Candelino Amin Mehrvarz Nader Jalili |
| author_facet | Mohammad Javad Khodaei Nicholas Candelino Amin Mehrvarz Nader Jalili |
| author_sort | Mohammad Javad Khodaei |
| collection | DOAJ |
| description | Over the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of physiological closed-loop control systems (PCLCs). Today, multidisciplinary groups of expert scientists, engineers, clinicians, mathematicians, and policy-makers are combining their knowledge and experience to develop both the next generation of PCLC-based medical equipment and a collaborative commercial/academic infrastructure to support this rapidly expanding frontier. In the following article, we provide a robust introduction to the various aspects of this growing field motivated by the recent and ongoing work supporting two leading technologies: the artificial pancreas (AP) and automated anesthesia. Following a brief high-level overview of the main concepts in automated therapy and some relevant tools from systems and control theory, we explore - separately - the developments, challenges, state-of-the-art, and probable directions for AP and automated anesthesia systems. We then close the review with a consideration of the common lessons gleaned from these ventures and the implications they present for future investigations and adjacent research. |
| first_indexed | 2024-12-20T05:18:40Z |
| format | Article |
| id | doaj.art-13bc86fbfdd0429089ccf9a8409c39b6 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-12-20T05:18:40Z |
| publishDate | 2020-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-13bc86fbfdd0429089ccf9a8409c39b62022-12-21T19:52:05ZengIEEEIEEE Access2169-35362020-01-018239652400510.1109/ACCESS.2020.29684408964302Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in AutomationMohammad Javad Khodaei0https://orcid.org/0000-0002-2204-937XNicholas Candelino1https://orcid.org/0000-0003-4464-9752Amin Mehrvarz2https://orcid.org/0000-0003-3996-9348Nader Jalili3https://orcid.org/0000-0002-0868-801XDepartment of Mechanical and Industrial Engineering, Piezoactive Systems Laboratory, Northeastern University, Boston, MA, USADepartment of Mechanical and Industrial Engineering, Piezoactive Systems Laboratory, Northeastern University, Boston, MA, USADepartment of Mechanical and Industrial Engineering, Piezoactive Systems Laboratory, Northeastern University, Boston, MA, USADepartment of Mechanical and Industrial Engineering, Piezoactive Systems Laboratory, Northeastern University, Boston, MA, USAOver the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of physiological closed-loop control systems (PCLCs). Today, multidisciplinary groups of expert scientists, engineers, clinicians, mathematicians, and policy-makers are combining their knowledge and experience to develop both the next generation of PCLC-based medical equipment and a collaborative commercial/academic infrastructure to support this rapidly expanding frontier. In the following article, we provide a robust introduction to the various aspects of this growing field motivated by the recent and ongoing work supporting two leading technologies: the artificial pancreas (AP) and automated anesthesia. Following a brief high-level overview of the main concepts in automated therapy and some relevant tools from systems and control theory, we explore - separately - the developments, challenges, state-of-the-art, and probable directions for AP and automated anesthesia systems. We then close the review with a consideration of the common lessons gleaned from these ventures and the implications they present for future investigations and adjacent research.https://ieeexplore.ieee.org/document/8964302/Adaptive controlartificial intelligenceanesthesiaartificial pancreasautomated anesthesiaautomation |
| spellingShingle | Mohammad Javad Khodaei Nicholas Candelino Amin Mehrvarz Nader Jalili Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation IEEE Access Adaptive control artificial intelligence anesthesia artificial pancreas automated anesthesia automation |
| title | Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation |
| title_full | Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation |
| title_fullStr | Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation |
| title_full_unstemmed | Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation |
| title_short | Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation |
| title_sort | physiological closed loop control pclc systems review of a modern frontier in automation |
| topic | Adaptive control artificial intelligence anesthesia artificial pancreas automated anesthesia automation |
| url | https://ieeexplore.ieee.org/document/8964302/ |
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