Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic.
<h4>Background</h4>There is a need to understand the impact of COVID-19 on colorectal cancer care globally and determine drivers of variation.<h4>Objective</h4>To evaluate COVID-19 impact on colorectal cancer services globally and identify predictors for behaviour change.<...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0240397 |
| _version_ | 1818725697192984576 |
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| author | Sam E Mason Alasdair J Scott Sheraz R Markar Jonathan M Clarke Guy Martin Jasmine Winter Beatty Viknesh Sounderajah Seema Yalamanchili Max Denning Thanjakumar Arulampalam James M Kinross PanSurg Collaborative |
| author_facet | Sam E Mason Alasdair J Scott Sheraz R Markar Jonathan M Clarke Guy Martin Jasmine Winter Beatty Viknesh Sounderajah Seema Yalamanchili Max Denning Thanjakumar Arulampalam James M Kinross PanSurg Collaborative |
| author_sort | Sam E Mason |
| collection | DOAJ |
| description | <h4>Background</h4>There is a need to understand the impact of COVID-19 on colorectal cancer care globally and determine drivers of variation.<h4>Objective</h4>To evaluate COVID-19 impact on colorectal cancer services globally and identify predictors for behaviour change.<h4>Design</h4>An online survey of colorectal cancer service change globally in May and June 2020.<h4>Participants</h4>Attending or consultant surgeons involved in the care of patients with colorectal cancer.<h4>Main outcome measures</h4>Changes in the delivery of diagnostics (diagnostic endoscopy), imaging for staging, therapeutics and surgical technique in the management of colorectal cancer. Predictors of change included increased hospital bed stress, critical care bed stress, mortality and world region.<h4>Results</h4>191 responses were included from surgeons in 159 centers across 46 countries, demonstrating widespread service reduction with global variation. Diagnostic endoscopy was reduced in 93% of responses, even with low hospital stress and mortality; whilst rising critical care bed stress triggered complete cessation (p = 0.02). Availability of CT and MRI fell by 40-41%, with MRI significantly reduced with high hospital stress. Neoadjuvant therapy use in rectal cancer changed in 48% of responses, where centers which had ceased surgery increased its use (62 vs 30%, p = 0.04) as did those with extended delays to surgery (p<0.001). High hospital and critical care bed stresses were associated with surgeons forming more stomas (p<0.04), using more experienced operators (p<0.003) and decreased laparoscopy use (critical care bed stress only, p<0.001). Patients were also more actively prioritized for resection, with increased importance of co-morbidities and ICU need.<h4>Conclusions</h4>The COVID-19 pandemic was associated with severe restrictions in the availability of colorectal cancer services on a global scale, with significant variation in behaviours which cannot be fully accounted for by hospital burden or mortality. |
| first_indexed | 2024-12-17T21:46:25Z |
| format | Article |
| id | doaj.art-13be5ee830244ff28013b373307ea840 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T21:46:25Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-13be5ee830244ff28013b373307ea8402022-12-21T21:31:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e024039710.1371/journal.pone.0240397Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic.Sam E MasonAlasdair J ScottSheraz R MarkarJonathan M ClarkeGuy MartinJasmine Winter BeattyViknesh SounderajahSeema YalamanchiliMax DenningThanjakumar ArulampalamJames M KinrossPanSurg Collaborative<h4>Background</h4>There is a need to understand the impact of COVID-19 on colorectal cancer care globally and determine drivers of variation.<h4>Objective</h4>To evaluate COVID-19 impact on colorectal cancer services globally and identify predictors for behaviour change.<h4>Design</h4>An online survey of colorectal cancer service change globally in May and June 2020.<h4>Participants</h4>Attending or consultant surgeons involved in the care of patients with colorectal cancer.<h4>Main outcome measures</h4>Changes in the delivery of diagnostics (diagnostic endoscopy), imaging for staging, therapeutics and surgical technique in the management of colorectal cancer. Predictors of change included increased hospital bed stress, critical care bed stress, mortality and world region.<h4>Results</h4>191 responses were included from surgeons in 159 centers across 46 countries, demonstrating widespread service reduction with global variation. Diagnostic endoscopy was reduced in 93% of responses, even with low hospital stress and mortality; whilst rising critical care bed stress triggered complete cessation (p = 0.02). Availability of CT and MRI fell by 40-41%, with MRI significantly reduced with high hospital stress. Neoadjuvant therapy use in rectal cancer changed in 48% of responses, where centers which had ceased surgery increased its use (62 vs 30%, p = 0.04) as did those with extended delays to surgery (p<0.001). High hospital and critical care bed stresses were associated with surgeons forming more stomas (p<0.04), using more experienced operators (p<0.003) and decreased laparoscopy use (critical care bed stress only, p<0.001). Patients were also more actively prioritized for resection, with increased importance of co-morbidities and ICU need.<h4>Conclusions</h4>The COVID-19 pandemic was associated with severe restrictions in the availability of colorectal cancer services on a global scale, with significant variation in behaviours which cannot be fully accounted for by hospital burden or mortality.https://doi.org/10.1371/journal.pone.0240397 |
| spellingShingle | Sam E Mason Alasdair J Scott Sheraz R Markar Jonathan M Clarke Guy Martin Jasmine Winter Beatty Viknesh Sounderajah Seema Yalamanchili Max Denning Thanjakumar Arulampalam James M Kinross PanSurg Collaborative Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. PLoS ONE |
| title | Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. |
| title_full | Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. |
| title_fullStr | Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. |
| title_full_unstemmed | Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. |
| title_short | Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. |
| title_sort | insights from a global snapshot of the change in elective colorectal practice due to the covid 19 pandemic |
| url | https://doi.org/10.1371/journal.pone.0240397 |
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