3D Melanoma Cocultures as Improved Models for Nanoparticle-Mediated Delivery of RNA to Tumors

3D Melanoma Cocultures as Improved Models for Nanoparticle-Mediated Delivery of RNA to Tumors

Cancer therapy is an emergent application for mRNA therapeutics. While in tumor immunotherapy, mRNA encoding for tumor-associated antigens is delivered to antigen-presenting cells in spleen and lymph nodes, other therapeutic options benefit from immediate delivery of mRNA nanomedicines directly to t...

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Bibliographic Details
Main Authors: Maximilian E. A. Schäfer, Florian Keller, Jens Schumacher, Heinrich Haas, Fulvia Vascotto, Ugur Sahin, Mathias Hafner, Rüdiger Rudolf
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
lipoplex
mRNA
nanoparticles
cancer
tumor targeting
tumor models
Online Access:https://www.mdpi.com/2073-4409/11/6/1026

Internet

https://www.mdpi.com/2073-4409/11/6/1026

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