Neural basis of the time window for subjective motor-auditory integration

Temporal contiguity between an action and corresponding auditory feedback is crucial to the perception of self-generated sound. However, the neural mechanisms underlying motor–auditory temporal integration are unclear. Here, we conducted four experiments with an oddball paradigm to examine the speci...

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Main Authors: Koichi eToida, Kanako eUeno, Sotaro eShimada
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00688/full
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author Koichi eToida
Koichi eToida
Kanako eUeno
Kanako eUeno
Sotaro eShimada
Sotaro eShimada
author_facet Koichi eToida
Koichi eToida
Kanako eUeno
Kanako eUeno
Sotaro eShimada
Sotaro eShimada
author_sort Koichi eToida
collection DOAJ
description Temporal contiguity between an action and corresponding auditory feedback is crucial to the perception of self-generated sound. However, the neural mechanisms underlying motor–auditory temporal integration are unclear. Here, we conducted four experiments with an oddball paradigm to examine the specific event-related potentials (ERPs) elicited by delayed auditory feedback for a self-generated action. The first experiment confirmed that a pitch-deviant auditory stimulus elicits mismatch negativity (MMN) and P300, both when it is generated passively and by the participant’s action. In our second and third experiments, we investigated the ERP components elicited by delayed auditory feedback of for a self-generated action. We found that delayed auditory feedback elicited an enhancement of P2 (enhanced-P2) and a N300 component, which were apparently different from the MMN and P300 components observed in the first experiment. We further investigated the sensitivity of the enhanced-P2 and N300 to delay length in our fourth experiment. Strikingly, the amplitude of the N300 increased as a function of the delay length. Additionally, the N300 amplitude was significantly correlated with the conscious detection of the delay (the 50% detection point was around 200 ms), and hence reduction in the feeling of authorship of the sound (the sense of agency). In contrast, the enhanced-P2 was most prominent in short-delay (≤ 200 ms) conditions and diminished in long-delay conditions. Our results suggest that different neural mechanisms are employed for the processing of temporally-deviant and pitch-deviant auditory feedback. Additionally, the temporal window for subjective motor–auditory integration is likely about 200 ms, as indicated by these auditory ERP components.
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spelling doaj.art-13c186dc9b994adead821178c6735da92022-12-21T19:51:59ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612016-01-01910.3389/fnhum.2015.00688157205Neural basis of the time window for subjective motor-auditory integrationKoichi eToida0Koichi eToida1Kanako eUeno2Kanako eUeno3Sotaro eShimada4Sotaro eShimada5Meiji UniversityJapan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST)Meiji UniversityJapan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST)Meiji UniversityJapan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST)Temporal contiguity between an action and corresponding auditory feedback is crucial to the perception of self-generated sound. However, the neural mechanisms underlying motor–auditory temporal integration are unclear. Here, we conducted four experiments with an oddball paradigm to examine the specific event-related potentials (ERPs) elicited by delayed auditory feedback for a self-generated action. The first experiment confirmed that a pitch-deviant auditory stimulus elicits mismatch negativity (MMN) and P300, both when it is generated passively and by the participant’s action. In our second and third experiments, we investigated the ERP components elicited by delayed auditory feedback of for a self-generated action. We found that delayed auditory feedback elicited an enhancement of P2 (enhanced-P2) and a N300 component, which were apparently different from the MMN and P300 components observed in the first experiment. We further investigated the sensitivity of the enhanced-P2 and N300 to delay length in our fourth experiment. Strikingly, the amplitude of the N300 increased as a function of the delay length. Additionally, the N300 amplitude was significantly correlated with the conscious detection of the delay (the 50% detection point was around 200 ms), and hence reduction in the feeling of authorship of the sound (the sense of agency). In contrast, the enhanced-P2 was most prominent in short-delay (≤ 200 ms) conditions and diminished in long-delay conditions. Our results suggest that different neural mechanisms are employed for the processing of temporally-deviant and pitch-deviant auditory feedback. Additionally, the temporal window for subjective motor–auditory integration is likely about 200 ms, as indicated by these auditory ERP components.http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00688/fullsense of agencydelayed auditory feedbackevent-related potential (ERP)N300enhanced-P2
spellingShingle Koichi eToida
Koichi eToida
Kanako eUeno
Kanako eUeno
Sotaro eShimada
Sotaro eShimada
Neural basis of the time window for subjective motor-auditory integration
Frontiers in Human Neuroscience
sense of agency
delayed auditory feedback
event-related potential (ERP)
N300
enhanced-P2
title Neural basis of the time window for subjective motor-auditory integration
title_full Neural basis of the time window for subjective motor-auditory integration
title_fullStr Neural basis of the time window for subjective motor-auditory integration
title_full_unstemmed Neural basis of the time window for subjective motor-auditory integration
title_short Neural basis of the time window for subjective motor-auditory integration
title_sort neural basis of the time window for subjective motor auditory integration
topic sense of agency
delayed auditory feedback
event-related potential (ERP)
N300
enhanced-P2
url http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00688/full
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AT kanakoeueno neuralbasisofthetimewindowforsubjectivemotorauditoryintegration
AT sotaroeshimada neuralbasisofthetimewindowforsubjectivemotorauditoryintegration
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