Anticitrullinated antibodies recognize rheumatoid arthritis associated T-cell epitopes modified by bacterial L-asparaginase

Anticitrullinated antibodies recognize rheumatoid arthritis associated T-cell epitopes modified by bacterial L-asparaginase

Citrullinated proteins and anti-citrullinated protein antibodies (ACPAs) play an important role in the pathogenesis of rheumatoid arthritis (RA). It has been suggested that during inflammation or dysbiosis, bacteria could initiate production of ACPAs. Most patients with RA are seropositive for ACPAs...

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Bibliographic Details
Main Authors: Tsvetelina Batsalova, Ivanka Teneva, Krum Bardarov, Dzhemal Moten, Balik Dzhambazov
Format: Article
Language:English
Published: Termedia Publishing House 2023-09-01
Series:Central European Journal of Immunology
Subjects:
rheumatoid arthritis
pathogenesis
l-asparaginase
type ii collagen
t-cell epitopes
posttranslational modifications
anti-citrullinated protein antibodies (acpas)
Online Access:https://www.termedia.pl/Anticitrullinated-antibodies-recognize-rheumatoid-arthritis-associated-T-cell-epitopes-modified-by-bacterial-L-asparaginase,10,51466,1,1.html

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