Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database
Introduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescriptio...
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| Format: | Article |
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Frontiers Media S.A.
2021-11-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2021.762895/full |
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| author | Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii |
| author_facet | Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii |
| author_sort | Satoko Suzuki |
| collection | DOAJ |
| description | Introduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescription of Kampo medicines for pregnant women in Japan.Methods: Information on Kampo medicines prescribed during outpatient care and hospitalization of selected mothers from January 2005 to August 2016 were extracted from the Japan Medical Data Center (Tokyo, Japan), which is a large claims database.Results: Of the 33,941 subscribers identified from the database, 16,294 (48%) received at least one prescription of a Kampo medicine. Kakkonto was the formula most prescribed during the study period, followed by shoseiryuto and tokishakuyakusan. In the 180 days before pregnancy, the most prescribed medicine was tokishakuyakusan, followed by kakkonto and shoseiryuto. Shoseiryuto, tokishakuyakusan, and kakkonnto were the formulae most prescribed during pregnancy. The most prescribed medicines during the 180 days postpartum were kakkonto, shoseiryuto, and saireito.Conclusions: Information in the Japanese insurance system shows that Kampo medicines are often prescribed during pregnancy. Most of these prescriptions are generally used for the treatment of common cold. Tokishakuyakusan in particular is usually used in the treatment of various symptoms of pregnancy. Further research is needed to clarify the relationship between the use of Kampo medicines during pregnancy and adverse events in infants in Japan. |
| first_indexed | 2024-12-18T23:50:42Z |
| format | Article |
| id | doaj.art-13c348dd88dd473ab42867f04045f520 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-12-18T23:50:42Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Nutrition |
| spelling | doaj.art-13c348dd88dd473ab42867f04045f5202022-12-21T20:46:56ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2021-11-01810.3389/fnut.2021.762895762895Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health DatabaseSatoko Suzuki0Satoko Suzuki1Taku Obara2Taku Obara3Tomofumi Ishikawa4Aoi Noda5Aoi Noda6Fumiko Matsuzaki7Ryutaro Arita8Ryutaro Arita9Minoru Ohsawa10Minoru Ohsawa11Minoru Ohsawa12Nariyasu Mano13Akiko Kikuchi14Akiko Kikuchi15Shin Takayama16Shin Takayama17Tadashi Ishii18Tadashi Ishii19Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, JapanDivision of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, JapanLaboratory of Clinical Pharmacy, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, JapanDepartment of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, JapanDivision of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, JapanDivision of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, JapanDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Obstetrics and Gynecology, Tohoku University Hospital, Sendai, JapanDepartment of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, JapanDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, JapanDepartment of Kampo Medicine, Tohoku University Hospital, Sendai, JapanIntroduction: Traditional Japanese (Kampo) medicines are often prescribed for women in Japan before, during, and after pregnancy. However, detailed information on the actual frequency of use and safety of Kampo preparations during pregnancy is lacking.Aim: To investigate the frequency of prescription of Kampo medicines for pregnant women in Japan.Methods: Information on Kampo medicines prescribed during outpatient care and hospitalization of selected mothers from January 2005 to August 2016 were extracted from the Japan Medical Data Center (Tokyo, Japan), which is a large claims database.Results: Of the 33,941 subscribers identified from the database, 16,294 (48%) received at least one prescription of a Kampo medicine. Kakkonto was the formula most prescribed during the study period, followed by shoseiryuto and tokishakuyakusan. In the 180 days before pregnancy, the most prescribed medicine was tokishakuyakusan, followed by kakkonto and shoseiryuto. Shoseiryuto, tokishakuyakusan, and kakkonnto were the formulae most prescribed during pregnancy. The most prescribed medicines during the 180 days postpartum were kakkonto, shoseiryuto, and saireito.Conclusions: Information in the Japanese insurance system shows that Kampo medicines are often prescribed during pregnancy. Most of these prescriptions are generally used for the treatment of common cold. Tokishakuyakusan in particular is usually used in the treatment of various symptoms of pregnancy. Further research is needed to clarify the relationship between the use of Kampo medicines during pregnancy and adverse events in infants in Japan.https://www.frontiersin.org/articles/10.3389/fnut.2021.762895/fullherbal medicineJapanese traditional medicineKampo medicinepregnant womendatabase |
| spellingShingle | Satoko Suzuki Satoko Suzuki Taku Obara Taku Obara Tomofumi Ishikawa Aoi Noda Aoi Noda Fumiko Matsuzaki Ryutaro Arita Ryutaro Arita Minoru Ohsawa Minoru Ohsawa Minoru Ohsawa Nariyasu Mano Akiko Kikuchi Akiko Kikuchi Shin Takayama Shin Takayama Tadashi Ishii Tadashi Ishii Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database Frontiers in Nutrition herbal medicine Japanese traditional medicine Kampo medicine pregnant women database |
| title | Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database |
| title_full | Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database |
| title_fullStr | Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database |
| title_full_unstemmed | Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database |
| title_short | Prescription of Kampo Formulations for Pre-natal and Post-partum Women in Japan: Data From an Administrative Health Database |
| title_sort | prescription of kampo formulations for pre natal and post partum women in japan data from an administrative health database |
| topic | herbal medicine Japanese traditional medicine Kampo medicine pregnant women database |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2021.762895/full |
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