Dnmt3aa but Not Dnmt3ab Is Required for Maintenance of Gametogenesis in Nile Tilapia (<i>Oreochromis niloticus</i>)

Dnmt3aa but Not Dnmt3ab Is Required for Maintenance of Gametogenesis in Nile Tilapia (<i>Oreochromis niloticus</i>)

<i>Dnmt3a</i>, a de novo methyltransferase, is essential for mammalian germ line DNA methylation. Only one <i>Dnmt3a</i> is identified in mammals, and homozygous mutants of <i>Dnmt3a</i> are lethal, while two <i>Dnmt3a</i> paralogs, <i>dnmt3aa<...

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Bibliographic Details
Main Authors: Feilong Wang, Zuliang Qin, Zhiqiang Li, Shuangyi Yang, Tian Gao, Lina Sun, Deshou Wang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
Nile tilapia
DNA methylation
<i>Dnmt3a</i>
gonad development
gametogenesis
Online Access:https://www.mdpi.com/1422-0067/22/18/10170

Internet

https://www.mdpi.com/1422-0067/22/18/10170

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