Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management

Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management

Abstract Chordoid meningioma is a morphological variant of meningioma designated as WHO grade 2. However, the recurrence rates varied widely in different case series, and to date, a unifying molecular genetic signature has not been identified. Among 1897 meningiomas resected at our institution, we i...

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Bibliographic Details
Main Authors: Elena V. Daoud, Kelsey Zhu, Bruce Mickey, Hussein Mohamed, Mandisa Wen, Michael Delorenzo, Ivy Tran, Jonathan Serrano, Kimmo J. Hatanpaa, Jack M. Raisanen, Matija Snuderl, Chunyu Cai
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Acta Neuropathologica Communications
Subjects:
Chordoid meningioma
Global methylation profile
WHO grade
Prognosis
Atypical meningioma
Brain tumor
Online Access:https://doi.org/10.1186/s40478-022-01362-3

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