Naringenin Impedes the Differentiation of Mouse Hematopoietic Stem Cells Derived from Bone Marrow into Mature Dendritic Cells, thereby Prolonging Allograft Survival

Naringenin Impedes the Differentiation of Mouse Hematopoietic Stem Cells Derived from Bone Marrow into Mature Dendritic Cells, thereby Prolonging Allograft Survival

Background: The use of immature dendritic cells (imDCs) to induce donor-specific immunotolerance following in vivo stimulation is limited by their low rate of induction and their tendency to undergo maturation. We derived imDCs from bone marrow hematopoietic stem cells (HSCs-imDCs). We then tested t...

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Bibliographic Details
Main Authors: Puxun Tian, Xiaoyan Huang, Kun Zhu, Zhankui Jin, Yan Li, Bingxuan Zheng, Xiangrong Zhao, Yangmeng Feng, Qing Feng, Dongliang Li, Jiaojiao Wang, Cuixiang Xu
Format: Article
Language:English
Published: IMR Press 2023-05-01
Series:Frontiers in Bioscience-Landmark
Subjects:
naringenin
hematopoietic stem cells
immature dendritic cells
immune tolerance
skin graft
Online Access:https://www.imrpress.com/journal/FBL/28/5/10.31083/j.fbl2805091

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