miR-150 suppresses the proliferation and tumorigenicity of leukemia stem cells by targeting the Nanog signaling pathway

miR-150 suppresses the proliferation and tumorigenicity of leukemia stem cells by targeting the Nanog signaling pathway

Proliferation, a key feature of cancer cells, accounts for the majority of cancer-related diseases resulting in mortality. MicroRNAs (miRNAs) plays important post-transcriptional modulation roles by acting on multiple signaling pathways, but the underlying mechanism in proliferation and tumorigenici...

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Bibliographic Details
Main Authors: Dan-dan Xu, Peng-jun Zhou, Ying Wang, Yi Zhang, Rong Zhang, Li Zhang, Su-hong Chen, Bi-bo Ruan, Hai-peng Xu, Wu-yu Fu, Chao-zhi Hu, Lu Tian, Jin-hong Qin, Sheng Wang, Xiao Wang, Qiu-ying Liu, Zhe Ren, Xue-qui Gu, Yao-he Li, Zhong Liu, Yi Fei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
proliferation
nanog
Leukemia Stem Cells
Tumorigenicity
MiR-150
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00439/full

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