Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species.
<h4>Background</h4>Burkholderia sensu stricto is comprised mainly of opportunistic pathogens. This group is widely distributed in the environment but is especially important in clinical settings. In Mexico, few species have been correctly identified among patients, most often B. cepacia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-06-01
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| Series: | PLoS Neglected Tropical Diseases |
| Online Access: | https://doi.org/10.1371/journal.pntd.0009541 |
| _version_ | 1818587232541343744 |
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| author | Georgina Meza-Radilla Violeta Larios-Serrato Rigoberto Hernández-Castro J Antonio Ibarra Paulina Estrada-de Los Santos |
| author_facet | Georgina Meza-Radilla Violeta Larios-Serrato Rigoberto Hernández-Castro J Antonio Ibarra Paulina Estrada-de Los Santos |
| author_sort | Georgina Meza-Radilla |
| collection | DOAJ |
| description | <h4>Background</h4>Burkholderia sensu stricto is comprised mainly of opportunistic pathogens. This group is widely distributed in the environment but is especially important in clinical settings. In Mexico, few species have been correctly identified among patients, most often B. cepacia is described.<h4>Methodology/principal findings</h4>In this study, approximately 90 strains identified as B. cepacia with the VITEK2 system were isolated from two medical centers in Mexico City and analyzed by MLSA, BOX-PCR and genome analysis. The initial identification of B. cepacia was confirmed for many strains, but B. contaminans, B. multivorans and B. vietnamiensis were also identified among clinical strains for the first time in hospitals in Mexico. Additionally, the presence of B. pseudomallei was confirmed, and a novel species within the B. cepacia complex was documented. Several strains misidentified as B. cepacia actually belong to the genera Pseudomonas, Stenotrophomonas and Providencia.<h4>Conclusions/significance</h4>The presence of different Burkholderia species in Mexico was confirmed. Correct identification of Burkholderia species is important to provide accurate treatment for immunosuppressed patients. |
| first_indexed | 2024-12-16T09:05:35Z |
| format | Article |
| id | doaj.art-13d219ba76854f3395ea5a0116141c71 |
| institution | Directory Open Access Journal |
| issn | 1935-2727 1935-2735 |
| language | English |
| last_indexed | 2024-12-16T09:05:35Z |
| publishDate | 2021-06-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Neglected Tropical Diseases |
| spelling | doaj.art-13d219ba76854f3395ea5a0116141c712022-12-21T22:37:04ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352021-06-01156e000954110.1371/journal.pntd.0009541Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species.Georgina Meza-RadillaVioleta Larios-SerratoRigoberto Hernández-CastroJ Antonio IbarraPaulina Estrada-de Los Santos<h4>Background</h4>Burkholderia sensu stricto is comprised mainly of opportunistic pathogens. This group is widely distributed in the environment but is especially important in clinical settings. In Mexico, few species have been correctly identified among patients, most often B. cepacia is described.<h4>Methodology/principal findings</h4>In this study, approximately 90 strains identified as B. cepacia with the VITEK2 system were isolated from two medical centers in Mexico City and analyzed by MLSA, BOX-PCR and genome analysis. The initial identification of B. cepacia was confirmed for many strains, but B. contaminans, B. multivorans and B. vietnamiensis were also identified among clinical strains for the first time in hospitals in Mexico. Additionally, the presence of B. pseudomallei was confirmed, and a novel species within the B. cepacia complex was documented. Several strains misidentified as B. cepacia actually belong to the genera Pseudomonas, Stenotrophomonas and Providencia.<h4>Conclusions/significance</h4>The presence of different Burkholderia species in Mexico was confirmed. Correct identification of Burkholderia species is important to provide accurate treatment for immunosuppressed patients.https://doi.org/10.1371/journal.pntd.0009541 |
| spellingShingle | Georgina Meza-Radilla Violeta Larios-Serrato Rigoberto Hernández-Castro J Antonio Ibarra Paulina Estrada-de Los Santos Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. PLoS Neglected Tropical Diseases |
| title | Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. |
| title_full | Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. |
| title_fullStr | Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. |
| title_full_unstemmed | Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. |
| title_short | Burkholderia species in human infections in Mexico: Identification of B. cepacia, B. contaminans, B. multivorans, B. vietnamiensis,B. pseudomallei and a new Burkholderia species. |
| title_sort | burkholderia species in human infections in mexico identification of b cepacia b contaminans b multivorans b vietnamiensis b pseudomallei and a new burkholderia species |
| url | https://doi.org/10.1371/journal.pntd.0009541 |
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