Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells

Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells

Ginsenoside Rh3 (GRh3) is a seminatural product obtained by chemical processing after isolation from Chinese herbal medicine that has strong antitumor activity against human tumors. However, its antitumor role remains to be elucidated. The aim of this study is to explore the mechanisms underlying th...

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Bibliographic Details
Main Authors: Wu Yingchao, Pi Dajin, Zhou Shuyao, Yi Zhongjia, Dong Yangyang, Wang Wuhong, Ye Huan, Chen Yiliu, Zuo Qian, Ouyang Mingzi
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-04-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
pyroptosis
ferroptosis
ginsenoside Rh3
Stat3/p53/NRF2 axis
colorectal cancer
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023068

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https://www.sciengine.com/doi/10.3724/abbs.2023068

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