Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution.

Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution.

BACKGROUND: MicroRNA (miRNA) are negative regulators of gene expression, capable of exerting pronounced influences upon the translation and stability of mRNA. They are potential regulators of normal mammary gland development and of the maintenance of mammary epithelial progenitor cells. This study w...

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Bibliographic Details
Main Authors: Sandrine Le Guillou, Nezha Sdassi, Johann Laubier, Bruno Passet, Marthe Vilotte, Johan Castille, Denis Laloë, Jacqueline Polyte, Stéphan Bouet, Florence Jaffrézic, Edmond-Paul Cribiu, Jean-Luc Vilotte, Fabienne Le Provost
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454336?pdf=render

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