A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults

A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adults

Despite high vaccination coverage worldwide, pertussis has re-emerged in many countries. This randomized, controlled, observer-blind phase I study and extension study in Belgium (March 2012–June 2015) assessed safety and immunogenicity of investigational acellular pertussis vaccines containing genet...

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Bibliographic Details
Main Authors: Geert Leroux-Roels, Maria Lattanzi, Claudia Dovali Solis, Mario Contorni, Marco Costantini, Luca Moraschini, Monia Bardelli, Sylvie Bertholet, Erica Borgogni, Francesca Buricchi, Rocco Cantisani, Elisa Faenzi, Oretta Finco, Rosanna Leuzzi, Mariagrazia Pizza, Domenico Rosa, Francesca Schiavetti, Anja Seubert, Fabiana Spensieri, Gianfranco Volpini, Luisanna Zedda, Giuseppe Del Giudice, Ilaria Galgani
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
adults
genetically detoxified pt
immunogenicity
persistence
pertussis
safety
Online Access:http://dx.doi.org/10.1080/21645515.2017.1385686

Internet

http://dx.doi.org/10.1080/21645515.2017.1385686

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