Prevalence, Patterns, and Genetic Association Analysis of Modic Vertebral Endplate Changes

Prevalence, Patterns, and Genetic Association Analysis of Modic Vertebral Endplate Changes

Study DesignA prospective genetic association study.PurposeThe etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However, studies with a larger patient subset are lacking, and candidate genes involved in other disc degenerati...

Full description

Bibliographic Details
Main Authors:	Rishi Mugesh Kanna, Rajasekaran Shanmuganathan, Veera Ranjani Rajagopalan, Senthil Natesan, Raveendran Muthuraja, Kenneth Man Chee Cheung, Danny Chan, Patrick Yu Ping Kao, Anita Yee, Ajoy Prasad Shetty
Format:	Article
Language:	English
Published:	Korean Spine Society 2017-08-01
Series:	Asian Spine Journal
Subjects:	Prevalence Modic changes Genetic association studies Single nucleotide polymorphism
Online Access:	http://www.asianspinejournal.org/upload/pdf/asj-11-594.pdf

Similar Items

Intervertebral disc degeneration and vertebral end plate damage in acute lumbar disc herniation
by: Arul P Nehru, et al.
Published: (2023-01-01)

The correlation between the change of Hounsfield units value and Modic changes in the lumbar vertebral endplate
by: Jiandong Zhu, et al.
Published: (2021-06-01)

Lubricin expression in the lumbar endplate and its association with Modic changes
by: Junhui Liu, et al.
Published: (2020-05-01)

The impact of dyslipidemia on lumbar intervertebral disc degeneration and vertebral endplate modic changes: a cross-sectional study of 1035 citizens in China
by: Liang Yuan, et al.
Published: (2023-07-01)

Modic changes in the cervical endplate of patients suffering from cervical spondylotic myelopathy
by: Pan Qiao, et al.
Published: (2018-04-01)

Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling Are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes)
by: Stefan Dudli, et al.
Published: (2020-05-01)

Modic changes in the lumbar vertebral column of chondrodystrophic and non-chondrodystrophic dogs with intervertebral disc disease
by: Dyah Agustini, et al.
Published: (2024-03-01)

Distribution of Modic changes in patients with low back pain and its related factors
by: Yufeng Chen, et al.
Published: (2019-10-01)

Spinopelvic alignment predicts disc calcification, displacement, and Modic changes: Evidence of an evolutionary etiology for clinically‐relevant spinal phenotypes
by: Uruj Zehra, et al.
Published: (2020-03-01)

The effect of zoledronic acid on type and volume of Modic changes among patients with low back pain
by: Katri Koivisto, et al.
Published: (2017-06-01)

Association of Modic Changes with Low Chronic Low Back Pain
by: Akbar Shah, et al.
Published: (2023-06-01)

The role of the complement system in disc degeneration and Modic changes
by: Irina Heggli, et al.
Published: (2024-03-01)

The Analysis of the Frequency of Schmorl’s Nodes on the Base of Modic Degeneration as Seen on the Lumbar Magnetic Resonance Imagings of the Cases with Lumbar Pain
by: Aysel Gürcan Atçı, et al.
Published: (2020-09-01)

The Relation Among Neck Pain, Modic Changes and Uncal Degeneration: An MRI Study
by: Muhittin Emre Altunrende, et al.
Published: (2019-12-01)

Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes
by: Martijn Beukers, et al.
Published: (2023-09-01)

Distribution of modic changes and its relation with age, sex and body mass index in Iranian population
by: Sheida Jahanbakhsi, et al.
Published: (2023-09-01)

Does bone scintigraphy show Modic changes associated with increased bone turnover?
by: Jyri Järvinen, et al.
Published: (2020-01-01)

The Prevalence of Lumbar Paraspinal Muscle Fatty Degeneration in Patients with Modic Type I and I/II End Plate Changes
by: Ibrahim Burak Atci, et al.
Published: (2020-04-01)

Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability
by: Lloyd G. Czaplewski, et al.
Published: (2023-05-01)

Exploring macrophage differentiation and its relation to Modic changes in human herniated disc tissue
by: N. Djuric, et al.
Published: (2022-01-01)

Automatic detection and voxel‐wise mapping of lumbar spine Modic changes with deep learning
by: Kenneth T. Gao, et al.
Published: (2022-06-01)

Asymmetrical degenerative marrow (Modic) changes in cervical spine: prevalence, correlative factors, and surgical outcomes
by: Xianda Gao, et al.
Published: (2018-04-01)

CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes
by: Stefan Dudli, et al.
Published: (2022-09-01)

Prevalence of and risk factors for Modic change in patients with symptomatic cervical spondylosis: an observational study
by: Bai J, et al.
Published: (2018-02-01)

Radiological outcomes of 360° lumbar fusion in patients with Modic changes
by: Evgenii S. Baikov, et al.
Published: (2022-10-01)

Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes
by: I. Heggli, et al.
Published: (2024-03-01)

Comparing image normalization techniques in an end-to-end model for automated modic changes classification from MRI images
by: Andrea Cina, et al.
Published: (2024-01-01)

Disc degeneration is easily occurred at the same and adjacent cephalad level in cervical spine when Modic changes are present
by: Junhui Liu, et al.
Published: (2023-07-01)

Placebo-controlled Trial of Oral Vitamin D and Alendronate Efficacy for Pain and Modic Changes in Lumbar Fusion Surgery
by: Kaveh Haddadi, et al.
Published: (2023-01-01)

The effects of lumbar fusion and non-fusion surgery on the development of Modic changes
by: Xiaoping Mu, et al.
Published: (2022-07-01)

Association between device-measured physical activity and lumbar Modic changes
by: Marella Modarress Julin, et al.
Published: (2020-09-01)

Study and analysis of the correlation between lumbar spondylolisthesis and Modic changes
by: Guang-qing Li, et al.
Published: (2024-02-01)

Relationship between vertebral endplate degeneration (Modic changes, Schmorl nodes, endplate irregularities) and Bone Mineral Density
by: Feirong Xu, et al.
Published: (2023-12-01)

Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
by: Bråten LCH, et al.
Published: (2023-05-01)

Impact of Acute Lumbar Disk Herniation on Sexual Function in Male Patients
by: Keerthivasan Panneerselvam, et al.
Published: (2022-08-01)

In Vertebral Hemangiomas with Neurological Deficit, Is a Less Extensive Approach Adequate?
by: K. Guna Pratheep, et al.
Published: (2023-02-01)

The Effect of Fusion Added to Lumbar Discectomy in Patients with Modic Changes: A Retrospective Comparative Outcome Analysis Regarding Back Pain Control
by: Ahmad Elsayed Desoukey Elayouty, MD.,, et al.
Published: (2018-10-01)

Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth
by: Tamara Mengis, et al.
Published: (2023-10-01)

Non-surgical therapy for the treatment of chronic low back pain in patients with Modic changes: A systematic review of the literature
by: Xiaoping Mu, et al.
Published: (2022-07-01)

Study of the Distribution of Lumbar Modic Changes in Patients with Low Back Pain and Correlation with Lumbar Degeneration Diseases
by: Wei B, et al.
Published: (2023-11-01)