In vitro and in silico studies reveal antidiabetic properties of arylbenzofurans from the root bark of Morus mesozygia Stapf

In vitro and in silico studies reveal antidiabetic properties of arylbenzofurans from the root bark of Morus mesozygia Stapf

Diabetes remains an important disease worldwide with about 500 million patients globally. In tropical Africa, Morus mesozygia is traditionally used in the treatment of diabetes. Biological and phytochemical investigation of the root bark extracts of the plant led to the isolation of a new prenylated...

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Bibliographic Details
Main Authors: Katherine Olabanjo Olufolabo, Kai Lüersen, Samuel Ayoolu Oguntimehin, Vaderament-A. Nchiozem-Ngnitedem, Emmanuel Ayodeji Agbebi, Kolade Olatubosun Faloye, Divinah Kwamboka Nyamboki, Gerald Rimbach, Josphat Clement Matasyoh, Bernd Schmidt, Jones Olanrewaju Moody
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
Morus mesozygia
African traditional medicine
root bark extract
arylbenzofuran
α-glucosidase
α-amylase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1338333/full

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