10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes

10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes

Jianxin Zhang,1 Chen Ming,2 Wenzhi Zhang,3 Patrick Nwabueze Okechukwu,4 Beata Morak-Młodawska,5 Krystian Pluta,5 Małgorzata Jeleń,5 Abdah Md Akim,6 Kok-Pian Ang,3 Kah Kooi Ooi6,71Department of Gynecology and Obstetrics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Beijing, 2Depar...

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Bibliographic Details
Main Authors: Zhang J, Ming C, Zhang W, Okechukwu PN, Morak-Młodawska B, Pluta K, Jeleń M, Akim AM, Ang KP, Ooi KK
Format: Article
Language:English
Published: Dove Medical Press 2017-10-01
Series:Drug Design, Development and Therapy
Subjects:
anticancer
programmed cell death
ovarian cancer
oxidative damage
mitochondrial function disruption
cancer cell invasion
Online Access:https://www.dovepress.com/10h-36-diazaphenothiazine--induces-g2m-phase-cell-cycle-arrest-and-cas-peer-reviewed-article-DDDT

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