High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum
Perineal leiomyosarcoma is an extremely rare and aggressive cancer with a high metastatic potential and no defined standard treatment. There are only a few (six) reported cases in the literature. We report the case of a 67-year-old woman with a perineal leiomyosarcoma arising at the same site of a p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2015-05-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/5875 |
| _version_ | 1818300941135249408 |
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| author | Neha Sood Abhisek Swaika Bashar Hanooshi James Waldorf Jennifer Peterson Kevin Wu Steven Attia Tri A. Dinh |
| author_facet | Neha Sood Abhisek Swaika Bashar Hanooshi James Waldorf Jennifer Peterson Kevin Wu Steven Attia Tri A. Dinh |
| author_sort | Neha Sood |
| collection | DOAJ |
| description | Perineal leiomyosarcoma is an extremely rare and aggressive cancer with a high metastatic potential and no defined standard treatment. There are only a few (six) reported cases in the literature. We report the case of a 67-year-old woman with a perineal leiomyosarcoma arising at the same site of a previously resected superficial angiomyxoma. Initially, she was treated for a presumptive recurrence of angiomyxoma. As she did not respond to medical therapy, she underwent repeat surgical excision. Pathology revealed a high grade leiomyosarcoma, histologically strikingly distinct from the initial diagnosis. She received adjuvant local radiation therapy, and remains without evidence of recurrent disease 36 months after completion of all therapy. This is the first reported case of a high grade perineal leiomyosarcoma originating at the same site as a resected benign superficial angiomyxoma. Our case emphasizes the necessity of a prompt histological diagnosis in cases of presumed recurrent perineal angiomyxoma. |
| first_indexed | 2024-12-13T05:15:07Z |
| format | Article |
| id | doaj.art-13e9c7556d784be7976d40349e5c6977 |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-13T05:15:07Z |
| publishDate | 2015-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-13e9c7556d784be7976d40349e5c69772022-12-21T23:58:27ZengSAGE PublishingRare Tumors2036-36052036-36132015-05-017210.4081/rt.2015.58753072High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineumNeha Sood0Abhisek Swaika1Bashar Hanooshi2James Waldorf3Jennifer Peterson4Kevin Wu5Steven Attia6Tri A. Dinh7Department of Medical and Surgical Gynecology, Mayo Clinic Florida, Jacksonville, FLDepartment of Medicine, Mayo Clinic Florida, Jacksonville, FLDepartment of Obstetrics and Gynecology, Flushing Hospital Medical Center, New York City, NYDepartment of Plastic Surgery, Mayo Clinic Florida, Jacksonville, FLDepartment of Radiation Oncology, Mayo Clinic Florida, Jacksonville, FLDepartment of Pathology, Mayo Clinic Florida, Jacksonville, FLDepartment of Medicine, Mayo Clinic Florida, Jacksonville, FLDepartment of Medical and Surgical Gynecology, Mayo Clinic Florida, Jacksonville, FLPerineal leiomyosarcoma is an extremely rare and aggressive cancer with a high metastatic potential and no defined standard treatment. There are only a few (six) reported cases in the literature. We report the case of a 67-year-old woman with a perineal leiomyosarcoma arising at the same site of a previously resected superficial angiomyxoma. Initially, she was treated for a presumptive recurrence of angiomyxoma. As she did not respond to medical therapy, she underwent repeat surgical excision. Pathology revealed a high grade leiomyosarcoma, histologically strikingly distinct from the initial diagnosis. She received adjuvant local radiation therapy, and remains without evidence of recurrent disease 36 months after completion of all therapy. This is the first reported case of a high grade perineal leiomyosarcoma originating at the same site as a resected benign superficial angiomyxoma. Our case emphasizes the necessity of a prompt histological diagnosis in cases of presumed recurrent perineal angiomyxoma.http://www.pagepress.org/journals/index.php/rt/article/view/5875Leiomyosarcomaangiomyxomaperineum |
| spellingShingle | Neha Sood Abhisek Swaika Bashar Hanooshi James Waldorf Jennifer Peterson Kevin Wu Steven Attia Tri A. Dinh High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum Rare Tumors Leiomyosarcoma angiomyxoma perineum |
| title | High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| title_full | High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| title_fullStr | High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| title_full_unstemmed | High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| title_short | High grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| title_sort | high grade leiomyosarcoma mimicking a recurrent angiomyxoma in the perineum |
| topic | Leiomyosarcoma angiomyxoma perineum |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/5875 |
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