Our experience of monitoring of drugs safety in gerontological practice

The analysis of work on identification and registration of complications of medicinal therapy in medical institutions of the Irkutsk region showed that the frequency of undesirable medicinal reactions at inpatients is more senior than 60 years makes from 10 % to 25 %. At advanced age the special pla...

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Main Authors: N. V. Verlan, E. O. Kochkina, A. V. Popadyuk
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2016-04-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/167
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author N. V. Verlan
E. O. Kochkina
A. V. Popadyuk
author_facet N. V. Verlan
E. O. Kochkina
A. V. Popadyuk
author_sort N. V. Verlan
collection DOAJ
description The analysis of work on identification and registration of complications of medicinal therapy in medical institutions of the Irkutsk region showed that the frequency of undesirable medicinal reactions at inpatients is more senior than 60 years makes from 10 % to 25 %. At advanced age the special place is taken by dysfunction of a digestive tract and allergic reactions at purpose of cardiovascular medicines, and also antibacterial and the antiglaucomous medicines. The number of cases of absence of therapeutic effect of PM in this age group made 18,9 %, reactions from the digestive tract - 15,5 % of cases, thus in 6,5 % pseudomembranous colitis was registered. It is established that risk factors of emergency of such reaction were the background pain or depressive syndrome, accompanying application of more than three drugs and absence of the scheme of a titration of dosages.
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spelling doaj.art-13ec4c17e1414df894ab2331f67cb95f2024-03-28T07:49:15ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-04-0112353810.12737/20612167Our experience of monitoring of drugs safety in gerontological practiceN. V. Verlan0E. O. Kochkina1A. V. Popadyuk2Irkutsk State Medical Academy of Continuing Education; Regional Center of Drug Safety MonitoringRegional Center of Drug Safety MonitoringRegional Center of Drug Safety MonitoringThe analysis of work on identification and registration of complications of medicinal therapy in medical institutions of the Irkutsk region showed that the frequency of undesirable medicinal reactions at inpatients is more senior than 60 years makes from 10 % to 25 %. At advanced age the special place is taken by dysfunction of a digestive tract and allergic reactions at purpose of cardiovascular medicines, and also antibacterial and the antiglaucomous medicines. The number of cases of absence of therapeutic effect of PM in this age group made 18,9 %, reactions from the digestive tract - 15,5 % of cases, thus in 6,5 % pseudomembranous colitis was registered. It is established that risk factors of emergency of such reaction were the background pain or depressive syndrome, accompanying application of more than three drugs and absence of the scheme of a titration of dosages.https://www.actabiomedica.ru/jour/article/view/167safety monitoringmedicineundesirable collateral reaction
spellingShingle N. V. Verlan
E. O. Kochkina
A. V. Popadyuk
Our experience of monitoring of drugs safety in gerontological practice
Acta Biomedica Scientifica
safety monitoring
medicine
undesirable collateral reaction
title Our experience of monitoring of drugs safety in gerontological practice
title_full Our experience of monitoring of drugs safety in gerontological practice
title_fullStr Our experience of monitoring of drugs safety in gerontological practice
title_full_unstemmed Our experience of monitoring of drugs safety in gerontological practice
title_short Our experience of monitoring of drugs safety in gerontological practice
title_sort our experience of monitoring of drugs safety in gerontological practice
topic safety monitoring
medicine
undesirable collateral reaction
url https://www.actabiomedica.ru/jour/article/view/167
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AT eokochkina ourexperienceofmonitoringofdrugssafetyingerontologicalpractice
AT avpopadyuk ourexperienceofmonitoringofdrugssafetyingerontologicalpractice