7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (<str...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-05-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2012/2/M756 |
| _version_ | 1811324108443484160 |
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| author | Ghulam Fareed Mahboob A. Kalhoro Muhammad A. Versiani Nighat Afza Nazia Fareed |
| author_facet | Ghulam Fareed Mahboob A. Kalhoro Muhammad A. Versiani Nighat Afza Nazia Fareed |
| author_sort | Ghulam Fareed |
| collection | DOAJ |
| description | Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (<strong>1</strong>) with 4-hydroxybenzaldehyde (<strong>2</strong>) in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, <sup>1</sup>H-NMR, and CHN techniques. |
| first_indexed | 2024-04-13T14:08:30Z |
| format | Article |
| id | doaj.art-13ecdfdda33e42dd97f8ed1b1f486bc5 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-04-13T14:08:30Z |
| publishDate | 2012-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-13ecdfdda33e42dd97f8ed1b1f486bc52022-12-22T02:43:51ZengMDPI AGMolbank1422-85992012-05-0120122M75610.3390/M7567-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic AcidGhulam FareedMahboob A. KalhoroMuhammad A. VersianiNighat AfzaNazia FareedNovel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (<strong>1</strong>) with 4-hydroxybenzaldehyde (<strong>2</strong>) in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, <sup>1</sup>H-NMR, and CHN techniques.http://www.mdpi.com/1422-8599/2012/2/M756ceftriaxone4-hydroxybenzaldehyde |
| spellingShingle | Ghulam Fareed Mahboob A. Kalhoro Muhammad A. Versiani Nighat Afza Nazia Fareed 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Molbank ceftriaxone 4-hydroxybenzaldehyde |
| title | 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| title_full | 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| title_fullStr | 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| title_full_unstemmed | 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| title_short | 7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid |
| title_sort | 7 2 4 hydroxyphenyl methylidene amino 1 3 thiazol 4 yl 2 methoxyimino acetyl amino 3 2 methyl 5 6 dioxo 1 2 5 6 tetrahydro 1 2 4 triazin 3 yl sulfanyl methyl 8 oxo 5 thia 1 azabicyclo 4 2 0 oct 2 ene 2 carboxylic acid |
| topic | ceftriaxone 4-hydroxybenzaldehyde |
| url | http://www.mdpi.com/1422-8599/2012/2/M756 |
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