Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities
The article is a comprehensive review concerning tetracyclic triterpene and steroid glycosides from sponges (Porifera, Demospongiae). The extensive oxidative transformations of the aglycone and the use of various monosaccharide residues, with up to six possible, are responsible for the significant s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/6/2503 |
| _version_ | 1797609897382117376 |
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| author | Natalia V. Ivanchina Vladimir I. Kalinin |
| author_facet | Natalia V. Ivanchina Vladimir I. Kalinin |
| author_sort | Natalia V. Ivanchina |
| collection | DOAJ |
| description | The article is a comprehensive review concerning tetracyclic triterpene and steroid glycosides from sponges (Porifera, Demospongiae). The extensive oxidative transformations of the aglycone and the use of various monosaccharide residues, with up to six possible, are responsible for the significant structural diversity observed in sponge saponins. The saponins are specific for different genera and species but their taxonomic distribution seems to be mosaic in different orders of Demospongiae. Many of the glycosides are membranolytics and possess cytotoxic activity that may be a cause of their anti-predatory activities. All these data reveal the independent origin and parallel evolution of the glycosides in different taxa of the sponges. The information concerning chemical structures, biological activities, biological role, and taxonomic distribution of the sponge glycosides is discussed. |
| first_indexed | 2024-03-11T06:08:00Z |
| format | Article |
| id | doaj.art-13f10fa434194d4a8822d92dbf434831 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T06:08:00Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-13f10fa434194d4a8822d92dbf4348312023-11-17T12:51:16ZengMDPI AGMolecules1420-30492023-03-01286250310.3390/molecules28062503Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological ActivitiesNatalia V. Ivanchina0Vladimir I. Kalinin1G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Sciences, Prospect 100 Letya Vladivostoka, 159, 690022 Vladivostok, RussiaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Sciences, Prospect 100 Letya Vladivostoka, 159, 690022 Vladivostok, RussiaThe article is a comprehensive review concerning tetracyclic triterpene and steroid glycosides from sponges (Porifera, Demospongiae). The extensive oxidative transformations of the aglycone and the use of various monosaccharide residues, with up to six possible, are responsible for the significant structural diversity observed in sponge saponins. The saponins are specific for different genera and species but their taxonomic distribution seems to be mosaic in different orders of Demospongiae. Many of the glycosides are membranolytics and possess cytotoxic activity that may be a cause of their anti-predatory activities. All these data reveal the independent origin and parallel evolution of the glycosides in different taxa of the sponges. The information concerning chemical structures, biological activities, biological role, and taxonomic distribution of the sponge glycosides is discussed.https://www.mdpi.com/1420-3049/28/6/2503tetracyclic triterpene glycosidessteroid glycosidestaxonomical distributionbiological rolebiological activitiesmarine sponges |
| spellingShingle | Natalia V. Ivanchina Vladimir I. Kalinin Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities Molecules tetracyclic triterpene glycosides steroid glycosides taxonomical distribution biological role biological activities marine sponges |
| title | Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities |
| title_full | Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities |
| title_fullStr | Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities |
| title_full_unstemmed | Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities |
| title_short | Triterpene and Steroid Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities |
| title_sort | triterpene and steroid glycosides from marine sponges porifera demospongiae structures taxonomical distribution biological activities |
| topic | tetracyclic triterpene glycosides steroid glycosides taxonomical distribution biological role biological activities marine sponges |
| url | https://www.mdpi.com/1420-3049/28/6/2503 |
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