Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton
Bone marrow stromal cells maintain the adult skeleton by forming osteoblasts throughout life that regenerate bone and repair fractures. We discovered that subsets of these stromal cells, osteoblasts, osteocytes, and hypertrophic chondrocytes secrete a C-type lectin domain protein, Clec11a, which pro...
Main Authors: | Rui Yue, Bo Shen, Sean J Morrison |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/18782 |
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