Disruption of Pituitary Gonadotrope Activity in Male Rats After Short- or Long-Term High-Fat Diets Is Not Associated With Pituitary Inflammation

Disruption of Pituitary Gonadotrope Activity in Male Rats After Short- or Long-Term High-Fat Diets Is Not Associated With Pituitary Inflammation

Overnutrition is associated with the activation of inflammatory pathways in metabolically linked organs and an early hypothalamic inflammation is now known to disrupt the central control of metabolic function. Because we demonstrated that fatty acids (FA) target the pituitary and affect gonadotropin...

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Bibliographic Details
Main Authors: Ghislaine Garrel, Claude Rouch, David L’Hôte, Salma Tazi, Nadim Kassis, Frank Giton, Julien Dairou, Pascal Dournaud, Pierre Gressens, Christophe Magnan, Céline Cruciani-Guglielmacci, Joëlle Cohen-Tannoudji
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Endocrinology
Subjects:
pituitary
inflammation
high-fat diet
gonadotropin
fatty acids
omega 3
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.877999/full

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